Binding studies of promethazine and its metabolites with human serum albumin by high-performance affinity chromatography and molecular docking in the presence of codeine.
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| Title: | Binding studies of promethazine and its metabolites with human serum albumin by high-performance affinity chromatography and molecular docking in the presence of codeine. |
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| Authors: | Coelho MM; Laboratory of Organic and Pharmaceutical Chemistry, Department of Chemical Sciences, Faculty of Pharmacy of the University of Porto, 4050-313, Porto, Portugal.; CIIMAR-Interdisciplinary Center for Marine and Environmental Research University of Porto, Porto de Leixões Cruise Terminal, 4450-208, Matosinhos, Portugal.; UCIBIO-Applied Molecular Biosciences Unit, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, 4050-313, Porto, Portugal., Lima R; Laboratory of Organic and Pharmaceutical Chemistry, Department of Chemical Sciences, Faculty of Pharmacy of the University of Porto, 4050-313, Porto, Portugal.; CIIMAR-Interdisciplinary Center for Marine and Environmental Research University of Porto, Porto de Leixões Cruise Terminal, 4450-208, Matosinhos, Portugal., Almeida AS; Laboratory of Organic and Pharmaceutical Chemistry, Department of Chemical Sciences, Faculty of Pharmacy of the University of Porto, 4050-313, Porto, Portugal.; CIIMAR-Interdisciplinary Center for Marine and Environmental Research University of Porto, Porto de Leixões Cruise Terminal, 4450-208, Matosinhos, Portugal.; UCIBIO-Applied Molecular Biosciences Unit, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, 4050-313, Porto, Portugal., Fernandes PA; LAQV, REQUIMTE, Departamento de Química E Bioquímica, Faculdade de Ciências, Universidade Do Porto, Rua Do Campo Alegre, S/N, 4169-007, Porto, Portugal., Remião F; UCIBIO-Applied Molecular Biosciences Unit, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, 4050-313, Porto, Portugal., Fernandes C; Laboratory of Organic and Pharmaceutical Chemistry, Department of Chemical Sciences, Faculty of Pharmacy of the University of Porto, 4050-313, Porto, Portugal. cfernandes@ff.up.pt.; CIIMAR-Interdisciplinary Center for Marine and Environmental Research University of Porto, Porto de Leixões Cruise Terminal, 4450-208, Matosinhos, Portugal. cfernandes@ff.up.pt., Tiritan ME; Laboratory of Organic and Pharmaceutical Chemistry, Department of Chemical Sciences, Faculty of Pharmacy of the University of Porto, 4050-313, Porto, Portugal. beth@ff.up.pt.; CIIMAR-Interdisciplinary Center for Marine and Environmental Research University of Porto, Porto de Leixões Cruise Terminal, 4450-208, Matosinhos, Portugal. beth@ff.up.pt.; 1H-TOXRUN - One Health Toxicology Research Unit, University Institute of Health Sciences (IUCS), CESPU, CRL, 4585-116, Gandra, Portugal. beth@ff.up.pt. |
| Source: | Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2024 Aug; Vol. 416 (20), pp. 4605-4618. Date of Electronic Publication: 2024 Jul 04. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 101134327 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-2650 (Electronic) Linking ISSN: 16182642 NLM ISO Abbreviation: Anal Bioanal Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1618-2650 |
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| DOI: | 10.1007/s00216-024-05409-3 |
