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Relevance of G protein-coupled receptor (GPCR) dynamics for receptor activation, signalling bias and allosteric modulation.

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Title: Relevance of G protein-coupled receptor (GPCR) dynamics for receptor activation, signalling bias and allosteric modulation.
Authors: Lopez-Balastegui M; Research Programme on Biomedical Informatics (GRIB), Hospital del Mar Medical Research Institute & Pompeu Fabra University, Barcelona, Spain., Stepniewski TM; Research Programme on Biomedical Informatics (GRIB), Hospital del Mar Medical Research Institute & Pompeu Fabra University, Barcelona, Spain.; InterAx Biotech AG, Villigen, Switzerland., Kogut-Günthel MM; Leibniz Institute for Food Systems Biology at the Technical University of Munich, Freising, Germany., Di Pizio A; Leibniz Institute for Food Systems Biology at the Technical University of Munich, Freising, Germany.; Chair for Chemoinformatics and Protein Modelling, Department of Molecular Life Science, School of Science, Technical University of Munich, Freising, Germany., Rosenkilde MM; Department of Biomedical Sciences, Faculty of Health and Medical Sciences University of Copenhagen, København N, Denmark., Mao J; Huairou Research Center, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China., Selent J; Research Programme on Biomedical Informatics (GRIB), Hospital del Mar Medical Research Institute & Pompeu Fabra University, Barcelona, Spain.
Source: British journal of pharmacology [Br J Pharmacol] 2025 Jul; Vol. 182 (14), pp. 3211-3224. Date of Electronic Publication: 2024 Jul 08.
Publication Type: Journal Article; Review
Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1476-5381
DOI:10.1111/bph.16495