Sleeping Beauty mRNA-LNP enables stable rAAV transgene expression in mouse and NHP hepatocytes and improves vector potency.
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| Title: | Sleeping Beauty mRNA-LNP enables stable rAAV transgene expression in mouse and NHP hepatocytes and improves vector potency. |
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| Authors: | Zakas PM; Tessera Therapeutics, Inc., Somerville, MA 02143, USA., Cunningham SC; Gene Therapy Research Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney and Sydney Children's Hospitals Network, Westmead, NSW 2145, Australia., Doherty A; Tessera Therapeutics, Inc., Somerville, MA 02143, USA., van Dijk EB; Gene Therapy Research Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney and Sydney Children's Hospitals Network, Westmead, NSW 2145, Australia., Ibraheim R; Tessera Therapeutics, Inc., Somerville, MA 02143, USA., Yu S; Tessera Therapeutics, Inc., Somerville, MA 02143, USA., Mekonnen BD; Tessera Therapeutics, Inc., Somerville, MA 02143, USA., Lang B; Tessera Therapeutics, Inc., Somerville, MA 02143, USA., English EJ; Tessera Therapeutics, Inc., Somerville, MA 02143, USA., Sun G; Tessera Therapeutics, Inc., Somerville, MA 02143, USA., Duncan MC; Tessera Therapeutics, Inc., Somerville, MA 02143, USA., Benczkowski MS; Tessera Therapeutics, Inc., Somerville, MA 02143, USA., Altshuler RC; Tessera Therapeutics, Inc., Somerville, MA 02143, USA., Singh MJ; Tessera Therapeutics, Inc., Somerville, MA 02143, USA., Kibbler ES; Tessera Therapeutics, Inc., Somerville, MA 02143, USA., Tonga GY; Tessera Therapeutics, Inc., Somerville, MA 02143, USA., Wang ZJ; Tessera Therapeutics, Inc., Somerville, MA 02143, USA., Wang ZJ; Tessera Therapeutics, Inc., Somerville, MA 02143, USA., Li G; Tessera Therapeutics, Inc., Somerville, MA 02143, USA., An D; Tessera Therapeutics, Inc., Somerville, MA 02143, USA., Rottman JB; Tessera Therapeutics, Inc., Somerville, MA 02143, USA., Bhavsar Y; Tessera Therapeutics, Inc., Somerville, MA 02143, USA., Purcell C; Tessera Therapeutics, Inc., Somerville, MA 02143, USA., Jain R; Tessera Therapeutics, Inc., Somerville, MA 02143, USA., Alberry R; Tessera Therapeutics, Inc., Somerville, MA 02143, USA., Roquet N; Tessera Therapeutics, Inc., Somerville, MA 02143, USA., Fu Y; Tessera Therapeutics, Inc., Somerville, MA 02143, USA., Citorik RJ; Tessera Therapeutics, Inc., Somerville, MA 02143, USA., Rubens JR; Tessera Therapeutics, Inc., Somerville, MA 02143, USA., Holmes MC; Tessera Therapeutics, Inc., Somerville, MA 02143, USA., Cotta-Ramusino C; Tessera Therapeutics, Inc., Somerville, MA 02143, USA., Querbes W; Tessera Therapeutics, Inc., Somerville, MA 02143, USA., Alexander IE; Gene Therapy Research Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney and Sydney Children's Hospitals Network, Westmead, NSW 2145, Australia; Discipline of Child and Adolescent Health, University of Sydney, Westmead, NSW 2145, Australia. Electronic address: ian.alexander@health.nsw.gov.au., Salomon WE; Tessera Therapeutics, Inc., Somerville, MA 02143, USA. Electronic address: wsalomon@tesseratx.com. |
| Source: | Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2024 Oct 02; Vol. 32 (10), pp. 3356-3371. Date of Electronic Publication: 2024 Jul 08. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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