Biomass specific perfusion rate as a control lever for the continuous manufacturing of biosimilar monoclonal antibodies from CHO cell cultures.

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Title: Biomass specific perfusion rate as a control lever for the continuous manufacturing of biosimilar monoclonal antibodies from CHO cell cultures.
Authors: Leong J; Bioprocessing Technology Institute (BTI), Agency for Science, Technology and Research (A*STAR), Singapore, Republic of Singapore., Tang WQ; Bioprocessing Technology Institute (BTI), Agency for Science, Technology and Research (A*STAR), Singapore, Republic of Singapore., Chng J; BiosanaProcess Pte. Ltd., Singapore, Republic of Singapore., Ler WX; Bioprocessing Technology Institute (BTI), Agency for Science, Technology and Research (A*STAR), Singapore, Republic of Singapore., Manan NA; BiosanaProcess Pte. Ltd., Singapore, Republic of Singapore., Sim LC; Bioprocessing Technology Institute (BTI), Agency for Science, Technology and Research (A*STAR), Singapore, Republic of Singapore., Zheng ZY; Bioprocessing Technology Institute (BTI), Agency for Science, Technology and Research (A*STAR), Singapore, Republic of Singapore., Zhang W; Bioprocessing Technology Institute (BTI), Agency for Science, Technology and Research (A*STAR), Singapore, Republic of Singapore., Walsh I; Bioprocessing Technology Institute (BTI), Agency for Science, Technology and Research (A*STAR), Singapore, Republic of Singapore., Zijlstra G; Sartorius Stedim Netherlands B.V., Rotterdam, The Netherlands., Pennings M; BiosanaPharma, Leiden, The Netherlands., Ng SK; Bioprocessing Technology Institute (BTI), Agency for Science, Technology and Research (A*STAR), Singapore, Republic of Singapore.
Source: Biotechnology journal [Biotechnol J] 2024 Jul; Vol. 19 (7), pp. e2400092.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-VCH Verlag Country of Publication: Germany NLM ID: 101265833 Publication Model: Print Cited Medium: Internet ISSN: 1860-7314 (Electronic) Linking ISSN: 18606768 NLM ISO Abbreviation: Biotechnol J Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1860-7314
DOI:10.1002/biot.202400092