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Phosphonodiamidate prodrugs of phosphoantigens (ProPAgens) exhibit potent Vγ9/Vδ2 T cell activation and eradication of cancer cells.

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Bibliographic Details
Title: Phosphonodiamidate prodrugs of phosphoantigens (ProPAgens) exhibit potent Vγ9/Vδ2 T cell activation and eradication of cancer cells.
Authors: Xu Q; School of Pharmacy and Pharmaceutical Sciences, Cardiff University Cardiff CF10 3NB UK MehellouY1@cardiff.ac.uk., Sharif M; Institute of Immunology and Immunotherapy, University of Birmingham Birmingham B15 2TT UK b.willcox@bham.ac.uk.; Cancer Immunology and Immunotherapy Centre, University of Birmingham Birmingham B15 2TT UK., James E; School of Pharmacy and Pharmaceutical Sciences, Cardiff University Cardiff CF10 3NB UK MehellouY1@cardiff.ac.uk., Dismorr JO; School of Chemistry, University of Birmingham Birmingham B15 2TT UK., Tucker JHR; School of Chemistry, University of Birmingham Birmingham B15 2TT UK., Willcox BE; Institute of Immunology and Immunotherapy, University of Birmingham Birmingham B15 2TT UK b.willcox@bham.ac.uk.; Cancer Immunology and Immunotherapy Centre, University of Birmingham Birmingham B15 2TT UK., Mehellou Y; School of Pharmacy and Pharmaceutical Sciences, Cardiff University Cardiff CF10 3NB UK MehellouY1@cardiff.ac.uk.; Medicines Discovery Institute, Cardiff University Cardiff CF10 3AT UK.
Source: RSC medicinal chemistry [RSC Med Chem] 2024 Jun 03; Vol. 15 (7), pp. 2462-2473. Date of Electronic Publication: 2024 Jun 03 (Print Publication: 2024).
Publication Type: Journal Article
Journal Info: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101759460 Publication Model: eCollection Cited Medium: Internet ISSN: 2632-8682 (Electronic) Linking ISSN: 26328682 NLM ISO Abbreviation: RSC Med Chem Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2632-8682
DOI:10.1039/d4md00208c