Towards combining backbone and sugar constraint in 3'-3' bis-phosphonate tethered 2'-4' bridged LNA oligonucleotide trimers.
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| Title: | Towards combining backbone and sugar constraint in 3'-3' bis-phosphonate tethered 2'-4' bridged LNA oligonucleotide trimers. |
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| Authors: | Duchamp E; Department of Chemistry, Université de Montréal Québec H3C 3J7 Canada stephen.hanessian@umontreal.ca., Vasquez G; Department of Medicinal Chemistry, Ionis Pharmaceuticals Carlsbad CA 92010 USA., Firoozi N; Department of Chemistry, Université de Montréal Québec H3C 3J7 Canada stephen.hanessian@umontreal.ca., Freestone GC; Department of Medicinal Chemistry, Ionis Pharmaceuticals Carlsbad CA 92010 USA., Oestergaard M; Department of Medicinal Chemistry, Ionis Pharmaceuticals Carlsbad CA 92010 USA., Seth PP; Alnylam Pharmaceuticals 675 West Kendall St Cambridge MA 0214 USA., Hanessian S; Department of Chemistry, Université de Montréal Québec H3C 3J7 Canada stephen.hanessian@umontreal.ca.; Department of Pharmaceutical Sciences, University of California Irvine CA 92697 USA. |
| Source: | RSC advances [RSC Adv] 2024 Jul 26; Vol. 14 (33), pp. 23583-23591. Date of Electronic Publication: 2024 Jul 26 (Print Publication: 2024). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101581657 Publication Model: eCollection Cited Medium: Internet ISSN: 2046-2069 (Electronic) Linking ISSN: 20462069 NLM ISO Abbreviation: RSC Adv Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 2046-2069 |
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| DOI: | 10.1039/d4ra04277h |