Single-mitochondrion sequencing uncovers distinct mutational patterns and heteroplasmy landscape in mouse astrocytes and neurons.
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| Title: | Single-mitochondrion sequencing uncovers distinct mutational patterns and heteroplasmy landscape in mouse astrocytes and neurons. |
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| Authors: | Kadam PS; Department of Pharmacology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Yang Z; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, 19104, USA., Lu Y; Department of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, 19104, USA., Zhu H; Department of Pharmacology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Atiyas Y; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, 19104, USA., Shah N; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, 19104, USA., Fisher S; Department of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, 19104, USA., Nordgren E; Department of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, 19104, USA., Kim J; Department of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, 19104, USA., Issadore D; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, 19104, USA. issadore@seas.upenn.edu., Eberwine J; Department of Pharmacology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. eberwine@pennmedicine.upenn.edu. |
| Source: | BMC biology [BMC Biol] 2024 Jul 29; Vol. 22 (1), pp. 162. Date of Electronic Publication: 2024 Jul 29. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101190720 Publication Model: Electronic Cited Medium: Internet ISSN: 1741-7007 (Electronic) Linking ISSN: 17417007 NLM ISO Abbreviation: BMC Biol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1741-7007 |
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| DOI: | 10.1186/s12915-024-01953-7 |
