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Single-mitochondrion sequencing uncovers distinct mutational patterns and heteroplasmy landscape in mouse astrocytes and neurons.

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Title: Single-mitochondrion sequencing uncovers distinct mutational patterns and heteroplasmy landscape in mouse astrocytes and neurons.
Authors: Kadam PS; Department of Pharmacology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Yang Z; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, 19104, USA., Lu Y; Department of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, 19104, USA., Zhu H; Department of Pharmacology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Atiyas Y; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, 19104, USA., Shah N; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, 19104, USA., Fisher S; Department of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, 19104, USA., Nordgren E; Department of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, 19104, USA., Kim J; Department of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, 19104, USA., Issadore D; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, 19104, USA. issadore@seas.upenn.edu., Eberwine J; Department of Pharmacology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. eberwine@pennmedicine.upenn.edu.
Source: BMC biology [BMC Biol] 2024 Jul 29; Vol. 22 (1), pp. 162. Date of Electronic Publication: 2024 Jul 29.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190720 Publication Model: Electronic Cited Medium: Internet ISSN: 1741-7007 (Electronic) Linking ISSN: 17417007 NLM ISO Abbreviation: BMC Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Single-mitochondrion sequencing uncovers distinct mutational patterns and heteroplasmy landscape in mouse astrocytes and neurons.
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  Data: <searchLink fieldCode="AU" term="%22Kadam+PS%22">Kadam PS</searchLink>; Department of Pharmacology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Yang+Z%22">Yang Z</searchLink>; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Lu+Y%22">Lu Y</searchLink>; Department of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Zhu+H%22">Zhu H</searchLink>; Department of Pharmacology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Atiyas+Y%22">Atiyas Y</searchLink>; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Shah+N%22">Shah N</searchLink>; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Fisher+S%22">Fisher S</searchLink>; Department of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Nordgren+E%22">Nordgren E</searchLink>; Department of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Kim+J%22">Kim J</searchLink>; Department of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Issadore+D%22">Issadore D</searchLink>; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, 19104, USA. issadore@seas.upenn.edu.<br /><searchLink fieldCode="AU" term="%22Eberwine+J%22">Eberwine J</searchLink>; Department of Pharmacology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. eberwine@pennmedicine.upenn.edu.
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  Data: <searchLink fieldCode="JN" term="%22101190720%22">BMC biology</searchLink> [BMC Biol] 2024 Jul 29; Vol. 22 (1), pp. 162. <i>Date of Electronic Publication: </i>2024 Jul 29.
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              Text: 2024 Jul 29
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