Novel imidazo[2,1-b]thiazoles and imidazo[1,2-a]pyridines tethered with indolinone motif as VEGFR-2 inhibitors and apoptotic inducers: Design, synthesis and biological evaluations.
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| Title: | Novel imidazo[2,1-b]thiazoles and imidazo[1,2-a]pyridines tethered with indolinone motif as VEGFR-2 inhibitors and apoptotic inducers: Design, synthesis and biological evaluations. |
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| Authors: | Elkotamy MS; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Egyptian-Russian University, Badr City 11829, Cairo, Egypt. Electronic address: mahmoud-elkotamy@eru.edu.eg., Elgohary MK; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Egyptian-Russian University, Badr City 11829, Cairo, Egypt., Al-Rashood ST; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia., Almahli H; Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK., Eldehna WM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh 33516, Egypt. Electronic address: wagdy2000@gmail.com., Abdel-Aziz HA; Applied Organic Chemistry Department, National Research Center, Dokki 12622, Cairo, Egypt; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Pharos University in Alexandria, Canal El Mahmoudia St., Alexandria 21648, Egypt. |
| Source: | Bioorganic chemistry [Bioorg Chem] 2024 Oct; Vol. 151, pp. 107644. Date of Electronic Publication: 2024 Jul 15. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 39079394 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Novel imidazo[2,1-b]thiazoles and imidazo[1,2-a]pyridines tethered with indolinone motif as VEGFR-2 inhibitors and apoptotic inducers: Design, synthesis and biological evaluations. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Elkotamy+MS%22">Elkotamy MS</searchLink>; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Egyptian-Russian University, Badr City 11829, Cairo, Egypt. Electronic address: mahmoud-elkotamy@eru.edu.eg.<br /><searchLink fieldCode="AU" term="%22Elgohary+MK%22">Elgohary MK</searchLink>; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Egyptian-Russian University, Badr City 11829, Cairo, Egypt.<br /><searchLink fieldCode="AU" term="%22Al-Rashood+ST%22">Al-Rashood ST</searchLink>; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Almahli+H%22">Almahli H</searchLink>; Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK.<br /><searchLink fieldCode="AU" term="%22Eldehna+WM%22">Eldehna WM</searchLink>; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh 33516, Egypt. Electronic address: wagdy2000@gmail.com.<br /><searchLink fieldCode="AU" term="%22Abdel-Aziz+HA%22">Abdel-Aziz HA</searchLink>; Applied Organic Chemistry Department, National Research Center, Dokki 12622, Cairo, Egypt; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Pharos University in Alexandria, Canal El Mahmoudia St., Alexandria 21648, Egypt. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%221303703%22">Bioorganic chemistry</searchLink> [Bioorg Chem] 2024 Oct; Vol. 151, pp. 107644. <i>Date of Electronic Publication: </i>2024 Jul 15. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>1303703 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1090-2120 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200452068%22">00452068 </searchLink><i>NLM ISO Abbreviation: </i>Bioorg Chem <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=39079394 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.bioorg.2024.107644 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 107644 Titles: – TitleFull: Novel imidazo[2,1-b]thiazoles and imidazo[1,2-a]pyridines tethered with indolinone motif as VEGFR-2 inhibitors and apoptotic inducers: Design, synthesis and biological evaluations. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Elkotamy MS – PersonEntity: Name: NameFull: Elgohary MK – PersonEntity: Name: NameFull: Al-Rashood ST – PersonEntity: Name: NameFull: Almahli H – PersonEntity: Name: NameFull: Eldehna WM – PersonEntity: Name: NameFull: Abdel-Aziz HA IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 10 Text: 2024 Oct Type: published Y: 2024 Identifiers: – Type: issn-electronic Value: 1090-2120 Numbering: – Type: volume Value: 151 Titles: – TitleFull: Bioorganic chemistry Type: main |
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