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Piplartine attenuates aminoglycoside-induced TRPV1 activity and protects from hearing loss in mice.

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Title: Piplartine attenuates aminoglycoside-induced TRPV1 activity and protects from hearing loss in mice.
Authors: Zallocchi M; Creighton University School of Medicine, Omaha, NE 68178, USA., Vijayakumar S; Creighton University School of Medicine, Omaha, NE 68178, USA., Fleegel J; Creighton University School of Medicine, Omaha, NE 68178, USA., Batalkina L; Creighton University School of Medicine, Omaha, NE 68178, USA., Brunette KE; Creighton University School of Medicine, Omaha, NE 68178, USA., Shukal D, Chen Z; Institute of Physiology, University of Zürich, Zürich CH-8057, Switzerland., Devuyst O; Institute of Physiology, University of Zürich, Zürich CH-8057, Switzerland., Liu H; Creighton University School of Medicine, Omaha, NE 68178, USA., He DZZ; Creighton University School of Medicine, Omaha, NE 68178, USA., Imami AS; Department of Neurosciences, University of Toledo, Toledo, OH 43614, USA., Hamoud AA; Department of Neurosciences, University of Toledo, Toledo, OH 43614, USA., McCullumsmith R; Department of Neurosciences, University of Toledo, Toledo, OH 43614, USA.; Neurosciences Institute, ProMedica, Toledo, OH 43614, USA., Conda-Sheridan M; University of Nebraska Medical Center, Omaha, NE 68198, USA., De Campos LJ; University of Nebraska Medical Center, Omaha, NE 68198, USA., Zuo J; Creighton University School of Medicine, Omaha, NE 68178, USA.; Ting Therapeutics LLC, La Jolla, CA 92037, USA.
Source: Science translational medicine [Sci Transl Med] 2024 Aug 07; Vol. 16 (759), pp. eadn2140. Date of Electronic Publication: 2024 Aug 07.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1946-6242
DOI:10.1126/scitranslmed.adn2140