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A Novel Combinatorial Regimen Using Sorafenib and Uttroside B, A US FDA-designated 'Orphan Drug', for the Treatment of Hepatocellular Carcinoma.

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Title: A Novel Combinatorial Regimen Using Sorafenib and Uttroside B, A US FDA-designated 'Orphan Drug', for the Treatment of Hepatocellular Carcinoma.
Authors: Keerthana CK; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, 695014, Kerala, India.; Department of Biotechnology, University of Kerala, Thiruvananthapuram, 695011, Kerala, India., Aiswarya SU; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, 695014, Kerala, India., Rayginia TP; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, 695014, Kerala, India.; Department of Biotechnology, University of Kerala, Thiruvananthapuram, 695011, Kerala, India., Vijayan Y; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, 695014, Kerala, India., James S; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, 695014, Kerala, India., Shifana SC; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, 695014, Kerala, India.; Molecular Bioassay Laboratory, Institute of Advanced Virology, Thonnakkal, Thiruvananthapuram, 695317, Kerala, India., Sundaram S; Department of Pathology, Government Medical College, Kottayam 686008, Kerala, India., Induja DK; Chemical Sciences and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram 695019, Kerala, India., Lankalapalli RS; Chemical Sciences and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram 695019, Kerala, India., Harikumar KB; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, 695014, Kerala, India., Anto RJ; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, 695014, Kerala, India.; Molecular Bioassay Laboratory, Institute of Advanced Virology, Thonnakkal, Thiruvananthapuram, 695317, Kerala, India.
Source: Anti-cancer agents in medicinal chemistry [Anticancer Agents Med Chem] 2024; Vol. 24 (19), pp. 1431-1441.
Publication Type: Journal Article
Journal Info: Publisher: Bentham Science Publishers Country of Publication: Netherlands NLM ID: 101265649 Publication Model: Print Cited Medium: Internet ISSN: 1875-5992 (Electronic) Linking ISSN: 18715206 NLM ISO Abbreviation: Anticancer Agents Med Chem Subsets: MEDLINE
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  Data: A Novel Combinatorial Regimen Using Sorafenib and Uttroside B, A US FDA-designated 'Orphan Drug', for the Treatment of Hepatocellular Carcinoma.
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  Data: <searchLink fieldCode="AU" term="%22Keerthana+CK%22">Keerthana CK</searchLink>; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, 695014, Kerala, India.; Department of Biotechnology, University of Kerala, Thiruvananthapuram, 695011, Kerala, India.<br /><searchLink fieldCode="AU" term="%22Aiswarya+SU%22">Aiswarya SU</searchLink>; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, 695014, Kerala, India.<br /><searchLink fieldCode="AU" term="%22Rayginia+TP%22">Rayginia TP</searchLink>; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, 695014, Kerala, India.; Department of Biotechnology, University of Kerala, Thiruvananthapuram, 695011, Kerala, India.<br /><searchLink fieldCode="AU" term="%22Vijayan+Y%22">Vijayan Y</searchLink>; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, 695014, Kerala, India.<br /><searchLink fieldCode="AU" term="%22James+S%22">James S</searchLink>; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, 695014, Kerala, India.<br /><searchLink fieldCode="AU" term="%22Shifana+SC%22">Shifana SC</searchLink>; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, 695014, Kerala, India.; Molecular Bioassay Laboratory, Institute of Advanced Virology, Thonnakkal, Thiruvananthapuram, 695317, Kerala, India.<br /><searchLink fieldCode="AU" term="%22Sundaram+S%22">Sundaram S</searchLink>; Department of Pathology, Government Medical College, Kottayam 686008, Kerala, India.<br /><searchLink fieldCode="AU" term="%22Induja+DK%22">Induja DK</searchLink>; Chemical Sciences and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram 695019, Kerala, India.<br /><searchLink fieldCode="AU" term="%22Lankalapalli+RS%22">Lankalapalli RS</searchLink>; Chemical Sciences and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram 695019, Kerala, India.<br /><searchLink fieldCode="AU" term="%22Harikumar+KB%22">Harikumar KB</searchLink>; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, 695014, Kerala, India.<br /><searchLink fieldCode="AU" term="%22Anto+RJ%22">Anto RJ</searchLink>; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, 695014, Kerala, India.; Molecular Bioassay Laboratory, Institute of Advanced Virology, Thonnakkal, Thiruvananthapuram, 695317, Kerala, India.
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