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Daily consumption of ketone ester, bis-octanoyl (R)-1,3-butanediol, is safe and tolerable in healthy older adults in a randomized, parallel arm, double-blind, placebo-controlled, pilot study.

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Title: Daily consumption of ketone ester, bis-octanoyl (R)-1,3-butanediol, is safe and tolerable in healthy older adults in a randomized, parallel arm, double-blind, placebo-controlled, pilot study.
Authors: Stubbs BJ; Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA 94945-1400, USA. Electronic address: bstubbs@buckinstitute.org., Stephens EB; Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA 94945-1400, USA., Senadheera C; Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA 94945-1400, USA., Peralta S; Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA 94945-1400, USA., Roa-Diaz S; Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA 94945-1400, USA., Alexander L; Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA 94945-1400, USA., Silverman-Martin W; Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA 94945-1400, USA., Garcia TY; Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA 94945-1400, USA., Yukawa M; Division of Geriatrics, UCSF, 3575 Geary Blvd, Fl 1, San Francisco, CA 94118-3212, USA; Geriatrics, San Francisco VA Medical Center, 4150 Clement St, San Francisco, CA 94121-1563, USA., Morris J; Geriatrics, San Francisco VA Medical Center, 4150 Clement St, San Francisco, CA 94121-1563, USA., Blonquist TM; Biofortis, Mérieux NutriSciences, 800-A South Rohling Rd, Addison, IL 60101-4219, USA., Johnson JB; Independent Researcher, Greenbrae, CA, USA., Newman JC; Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA 94945-1400, USA; Division of Geriatrics, UCSF, 3575 Geary Blvd, Fl 1, San Francisco, CA 94118-3212, USA. Electronic address: jnewman@buckinstitute.org.
Source: The journal of nutrition, health & aging [J Nutr Health Aging] 2024 Sep; Vol. 28 (9), pp. 100329. Date of Electronic Publication: 2024 Aug 12.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Elsevier Masson SAS on behalf of SERDI Publisher Country of Publication: France NLM ID: 100893366 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1760-4788 (Electronic) Linking ISSN: 12797707 NLM ISO Abbreviation: J Nutr Health Aging Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1760-4788
DOI:10.1016/j.jnha.2024.100329