The role of venous capacity in fluid retention with endothelin A antagonism: Mathematical modelling of the RADAR trial.
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| Title: | The role of venous capacity in fluid retention with endothelin A antagonism: Mathematical modelling of the RADAR trial. |
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| Authors: | Yu H; Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology and Safety Sciences, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, USA., Greasley PJ; Early Clinical Development, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Lambers Heerspink HJ; Department of Clinical Pharmacy and Pharmacology, University of Groningen, Groningen, The Netherlands.; The George Institute for Global Health, Sydney, Australia., Ambery P; Late-stage Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Ahlstrom C; Drug Metabolism and Pharmacokinetics, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Hamren B; Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Gothenburg, Sweden., Khan AA; Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology and Safety Sciences, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, USA., Boulton DW; Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology and Safety Sciences, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, USA., Hallow KM; School of Chemical, Materials, and Biomedical Engineering, University of Georgia, Athens, Georgia, USA.; Department of Epidemiology and Biostatistics, University of Georgia, Athens, Georgia, USA. |
| Source: | British journal of pharmacology [Br J Pharmacol] 2024 Nov; Vol. 181 (22), pp. 4693-4707. Date of Electronic Publication: 2024 Aug 19. |
| Publication Type: | Journal Article; Randomized Controlled Trial |
| Journal Info: | Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1476-5381 |
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| DOI: | 10.1111/bph.16504 |
