MicroRNAs modulate SARS-CoV-2 infection of primary human hepatocytes by regulating the entry factors ACE2 and TMPRSS2.
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| Title: | MicroRNAs modulate SARS-CoV-2 infection of primary human hepatocytes by regulating the entry factors ACE2 and TMPRSS2. |
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| Authors: | Khanal R; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany.; Research Group Liver Regeneration & RNA Therapeutics, REBIRTH-Research Center for Translational Regenerative Medicine, Hannover Medical School, Hannover, Germany., Heinen N; Department for Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany., Bogomolova A; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany.; Research Group Liver Regeneration & RNA Therapeutics, REBIRTH-Research Center for Translational Regenerative Medicine, Hannover Medical School, Hannover, Germany., Meister TL; Department for Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany.; Institute for Infection Research and Vaccine Development (IIRVD), Centre for Internal Medicine, University Medical Centre Hamburg-Eppendorf (UKE), Hamburg, Germany.; Department for Clinical Immunology of Infectious Diseases, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.; German Centre for Infection Research (DZIF), Partner Site Hamburg-Lübeck-Borstel-Riems, Hamburg, Germany., Herrmann ST; Department for Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany.; Research Unit Emerging Viruses, Leibniz Institute of Virology (LIV), Hamburg, Germany., Westhoven S; Department for Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany.; Research Unit Emerging Viruses, Leibniz Institute of Virology (LIV), Hamburg, Germany., Nocke MK; Department for Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany., Todt D; Department for Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany.; European Virus Bioinformatics Center (EVBC), Jena, Germany., Jockenhövel F; Department for Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany., Klein IM; Tissue Bank of the German Center for Infection Research (DZIF), Partner Site Heidelberg, Heidelberg, Germany.; Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany., Hartmann L; Tissue Bank of the German Center for Infection Research (DZIF), Partner Site Heidelberg, Heidelberg, Germany.; Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany., Vondran FWR; Department of General, Visceral, Pediatric and Transplant Surgery, University Hospital RWTH Aachen, Aachen, Germany., Steinmann E; Department for Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany., Zimmer G; Institute of Virology and Immunology, Bern, Switzerland.; Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland., Ott M; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany., Brown RJP; Department for Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany., Sharma AD; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany.; Research Group Liver Regeneration & RNA Therapeutics, REBIRTH-Research Center for Translational Regenerative Medicine, Hannover Medical School, Hannover, Germany., Pfaender S; Department for Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany.; Research Unit Emerging Viruses, Leibniz Institute of Virology (LIV), Hamburg, Germany.; University of Lübeck, Lübeck, Germany. |
| Source: | Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2024 Nov; Vol. 44 (11), pp. 2983-2995. Date of Electronic Publication: 2024 Aug 22. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 101160857 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1478-3231 (Electronic) Linking ISSN: 14783223 NLM ISO Abbreviation: Liver Int Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1478-3231 |
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| DOI: | 10.1111/liv.16079 |
