Schnurri-3 inhibition rescues skeletal fragility and vascular skeletal stem cell niche pathology in the OIM model of osteogenesis imperfecta.

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Title: Schnurri-3 inhibition rescues skeletal fragility and vascular skeletal stem cell niche pathology in the OIM model of osteogenesis imperfecta.
Authors: Li N; State Key Laboratory of Cellular Stress Biology, Cancer Research Center, School of Medicine, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, 361102, China.; Fujian Provincial Key Laboratory of Organ and Tissue Regeneration, School of Medicine, Xiamen University, Xiamen, 361102, China., Shi B; State Key Laboratory of Cellular Stress Biology, Cancer Research Center, School of Medicine, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, 361102, China.; Fujian Provincial Key Laboratory of Organ and Tissue Regeneration, School of Medicine, Xiamen University, Xiamen, 361102, China., Li Z; State Key Laboratory of Cellular Stress Biology, Cancer Research Center, School of Medicine, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, 361102, China.; Department of Sports Medicine, Xiangya Hospital, Central South University, Changsha, 410000, China., Han J; State Key Laboratory of Cellular Stress Biology, Cancer Research Center, School of Medicine, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, 361102, China., Sun J; Research Division, Hospital for Special Surgery, New York, NY, 10065, USA., Huang H; State Key Laboratory of Cellular Stress Biology, Cancer Research Center, School of Medicine, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, 361102, China., Yallowitz AR; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY, 10065, USA., Bok S; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY, 10065, USA., Xiao S; State Key Laboratory of Cellular Stress Biology, Cancer Research Center, School of Medicine, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, 361102, China., Wu Z; State Key Laboratory of Cellular Stress Biology, Cancer Research Center, School of Medicine, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, 361102, China., Chen Y; State Key Laboratory of Cellular Stress Biology, Cancer Research Center, School of Medicine, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, 361102, China., Xu Y; Department of Sports Medicine, Xiangya Hospital, Central South University, Changsha, 410000, China., Qin T; Department of Sports Medicine, Xiangya Hospital, Central South University, Changsha, 410000, China., Huang R; State Key Laboratory of Cellular Stress Biology, Cancer Research Center, School of Medicine, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, 361102, China., Zheng H; State Key Laboratory of Cellular Stress Biology, Cancer Research Center, School of Medicine, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, 361102, China.; Fujian Provincial Key Laboratory of Organ and Tissue Regeneration, School of Medicine, Xiamen University, Xiamen, 361102, China., Shen R; Fujian Provincial Key Laboratory of Organ and Tissue Regeneration, School of Medicine, Xiamen University, Xiamen, 361102, China., Meng L; Department of Electronic and Computer Engineering, Ritsumeikan University, Kusatsu, Shiga, 525-8577, Japan., Greenblatt MB; Research Division, Hospital for Special Surgery, New York, NY, 10065, USA. mag3003@med.cornell.edu.; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY, 10065, USA. mag3003@med.cornell.edu., Xu R; State Key Laboratory of Cellular Stress Biology, Cancer Research Center, School of Medicine, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, 361102, China. xuren526@xmu.edu.cn.; Fujian Provincial Key Laboratory of Organ and Tissue Regeneration, School of Medicine, Xiamen University, Xiamen, 361102, China. xuren526@xmu.edu.cn.
Source: Bone research [Bone Res] 2024 Aug 26; Vol. 12 (1), pp. 46. Date of Electronic Publication: 2024 Aug 26.
Publication Type: Journal Article
Journal Info: Publisher: West China School of Stomatology, Sichuan University Country of Publication: China NLM ID: 101608652 Publication Model: Electronic Cited Medium: Print ISSN: 2095-4700 (Print) Linking ISSN: 20954700 NLM ISO Abbreviation: Bone Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2095-4700
DOI:10.1038/s41413-024-00349-1