A cell state-specific metabolic vulnerability to GPX4-dependent ferroptosis in glioblastoma.
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| Title: | A cell state-specific metabolic vulnerability to GPX4-dependent ferroptosis in glioblastoma. |
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| Authors: | Banu MA; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA., Dovas A; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA., Argenziano MG; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA., Zhao W; Department of System Biology, Columbia University Irving Medical Center, New York, NY, USA., Sperring CP; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA., Cuervo Grajal H; Spanish National Center for Cardiovascular Research, Madrid, Spain., Liu Z; Department of System Biology, Columbia University Irving Medical Center, New York, NY, USA., Higgins DM; Department of Neurological Surgery, University of North Carolina School of Medicine, Chapel Hill, NC, USA., Amini M; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA., Pereira B; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA., Ye LF; Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA., Mahajan A; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA.; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA., Humala N; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA.; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA., Furnari JL; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA.; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA., Upadhyayula PS; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA., Zandkarimi F; Department of Biological Sciences, Department of Chemistry and Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, USA., Nguyen TT; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA., Teasley D; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA., Wu PB; Department of Neurological Surgery, UCLA Geffen School of Medicine, Los Angeles, CA, USA., Hai L; Sulzberger Columbia Genome Center, Columbia University, New York, NY, USA., Karan C; Sulzberger Columbia Genome Center, Columbia University, New York, NY, USA., Dowdy T; NCI Neuro-oncology Branch, Bethesda, MD, USA., Razavilar A; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA., Siegelin MD; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA., Kitajewski J; University of Illinois Cancer Center, Department of Physiology and Biophysics, University of Illinois Chicago, Chicago, IL, USA., Larion M; NCI Neuro-oncology Branch, Bethesda, MD, USA., Bruce JN; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA., Stockwell BR; Department of Biological Sciences, Department of Chemistry and Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, USA., Sims PA; Department of System Biology, Columbia University Irving Medical Center, New York, NY, USA. pas2182@cumc.columbia.edu., Canoll P; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA. pc561@cumc.columbia.edu.; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA. pc561@cumc.columbia.edu. |
| Source: | The EMBO journal [EMBO J] 2024 Oct; Vol. 43 (20), pp. 4492-4521. Date of Electronic Publication: 2024 Aug 27. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1460-2075 |
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| DOI: | 10.1038/s44318-024-00176-4 |
