View in EDS HTML Full Text PDF Full Text

Lactam Truncation Yields a Dihydroquinazolinone Scaffold with Potent Antimalarial Activity that Targets PfATP4.

Saved in:
Bibliographic Details
Title: Lactam Truncation Yields a Dihydroquinazolinone Scaffold with Potent Antimalarial Activity that Targets PfATP4.
Authors: Ashton TD; Walter and Eliza Hall Institute of Medical Research, Parkville, 3052, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, 3010, Victoria, Australia., Calic PPS; Walter and Eliza Hall Institute of Medical Research, Parkville, 3052, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, 3010, Victoria, Australia., Dans MG; Walter and Eliza Hall Institute of Medical Research, Parkville, 3052, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, 3010, Victoria, Australia., Kang Ooi Z; Walter and Eliza Hall Institute of Medical Research, Parkville, 3052, Victoria, Australia., Zhou Q; Walter and Eliza Hall Institute of Medical Research, Parkville, 3052, Victoria, Australia., Loi K; Walter and Eliza Hall Institute of Medical Research, Parkville, 3052, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, 3010, Victoria, Australia., Jarman KE; Walter and Eliza Hall Institute of Medical Research, Parkville, 3052, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, 3010, Victoria, Australia., Palandri J; Walter and Eliza Hall Institute of Medical Research, Parkville, 3052, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, 3010, Victoria, Australia., Qiu D; Research School of Biology, Australian National University, Canberra, 2601, Australia., Lehane AM; Research School of Biology, Australian National University, Canberra, 2601, Australia., Maity B; TCG Lifesciences, Kolkata, West Bengal, 700091, India., De N; TCG Lifesciences, Kolkata, West Bengal, 700091, India., Famodimu MT; Department of Infection Biology, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK., Delves MJ; Department of Infection Biology, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK., Mao EY; Research Centre for Infectious Diseases, School of Biological Sciences, University of Adelaide, Adelaide, 5005, Australia., Gancheva MR; Research Centre for Infectious Diseases, School of Biological Sciences, University of Adelaide, Adelaide, 5005, Australia., Wilson DW; Research Centre for Infectious Diseases, School of Biological Sciences, University of Adelaide, Adelaide, 5005, Australia., Chowdury M; School of Medicine, Deakin University, Waurn Ponds, Victoria, 3216, Australia.; Institute for Mental and Physical Health and Clinical Translation, Deakin University, Geelong, Victoria, 3216, Australia., de Koning-Ward TF; School of Medicine, Deakin University, Waurn Ponds, Victoria, 3216, Australia.; Institute for Mental and Physical Health and Clinical Translation, Deakin University, Geelong, Victoria, 3216, Australia., Baud D; MMV Medicines for Malaria Venture, ICC, Route de Pré-Bois 20, 1215, Geneva, Switzerland., Brand S; MMV Medicines for Malaria Venture, ICC, Route de Pré-Bois 20, 1215, Geneva, Switzerland., Jackson PF; Emerging Science & Innovation, Discovery Sciences, Janssen R&D LLC, La Jolla, California, 92121, USA., Cowman AF; Walter and Eliza Hall Institute of Medical Research, Parkville, 3052, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, 3010, Victoria, Australia., Sleebs BE; Walter and Eliza Hall Institute of Medical Research, Parkville, 3052, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, 3010, Victoria, Australia.
Source: ChemMedChem [ChemMedChem] 2024 Dec 16; Vol. 19 (24), pp. e202400549. Date of Electronic Publication: 2024 Oct 29.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101259013 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7187 (Electronic) Linking ISSN: 18607179 NLM ISO Abbreviation: ChemMedChem Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 39210733
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Lactam Truncation Yields a Dihydroquinazolinone Scaffold with Potent Antimalarial Activity that Targets PfATP4.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Ashton+TD%22">Ashton TD</searchLink>; Walter and Eliza Hall Institute of Medical Research, Parkville, 3052, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, 3010, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Calic+PPS%22">Calic PPS</searchLink>; Walter and Eliza Hall Institute of Medical Research, Parkville, 3052, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, 3010, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Dans+MG%22">Dans MG</searchLink>; Walter and Eliza Hall Institute of Medical Research, Parkville, 3052, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, 3010, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Kang+Ooi+Z%22">Kang Ooi Z</searchLink>; Walter and Eliza Hall Institute of Medical Research, Parkville, 3052, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Zhou+Q%22">Zhou Q</searchLink>; Walter and Eliza Hall Institute of Medical Research, Parkville, 3052, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Loi+K%22">Loi K</searchLink>; Walter and Eliza Hall Institute of Medical Research, Parkville, 3052, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, 3010, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Jarman+KE%22">Jarman KE</searchLink>; Walter and Eliza Hall Institute of Medical Research, Parkville, 3052, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, 3010, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Palandri+J%22">Palandri J</searchLink>; Walter and Eliza Hall Institute of Medical Research, Parkville, 3052, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, 3010, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Qiu+D%22">Qiu D</searchLink>; Research School of Biology, Australian National University, Canberra, 2601, Australia.<br /><searchLink fieldCode="AU" term="%22Lehane+AM%22">Lehane AM</searchLink>; Research School of Biology, Australian National University, Canberra, 2601, Australia.<br /><searchLink fieldCode="AU" term="%22Maity+B%22">Maity B</searchLink>; TCG Lifesciences, Kolkata, West Bengal, 700091, India.<br /><searchLink fieldCode="AU" term="%22De+N%22">De N</searchLink>; TCG Lifesciences, Kolkata, West Bengal, 700091, India.<br /><searchLink fieldCode="AU" term="%22Famodimu+MT%22">Famodimu MT</searchLink>; Department of Infection Biology, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK.<br /><searchLink fieldCode="AU" term="%22Delves+MJ%22">Delves MJ</searchLink>; Department of Infection Biology, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK.<br /><searchLink fieldCode="AU" term="%22Mao+EY%22">Mao EY</searchLink>; Research Centre for Infectious Diseases, School of Biological Sciences, University of Adelaide, Adelaide, 5005, Australia.<br /><searchLink fieldCode="AU" term="%22Gancheva+MR%22">Gancheva MR</searchLink>; Research Centre for Infectious Diseases, School of Biological Sciences, University of Adelaide, Adelaide, 5005, Australia.<br /><searchLink fieldCode="AU" term="%22Wilson+DW%22">Wilson DW</searchLink>; Research Centre for Infectious Diseases, School of Biological Sciences, University of Adelaide, Adelaide, 5005, Australia.<br /><searchLink fieldCode="AU" term="%22Chowdury+M%22">Chowdury M</searchLink>; School of Medicine, Deakin University, Waurn Ponds, Victoria, 3216, Australia.; Institute for Mental and Physical Health and Clinical Translation, Deakin University, Geelong, Victoria, 3216, Australia.<br /><searchLink fieldCode="AU" term="%22de+Koning-Ward+TF%22">de Koning-Ward TF</searchLink>; School of Medicine, Deakin University, Waurn Ponds, Victoria, 3216, Australia.; Institute for Mental and Physical Health and Clinical Translation, Deakin University, Geelong, Victoria, 3216, Australia.<br /><searchLink fieldCode="AU" term="%22Baud+D%22">Baud D</searchLink>; MMV Medicines for Malaria Venture, ICC, Route de Pré-Bois 20, 1215, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Brand+S%22">Brand S</searchLink>; MMV Medicines for Malaria Venture, ICC, Route de Pré-Bois 20, 1215, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Jackson+PF%22">Jackson PF</searchLink>; Emerging Science & Innovation, Discovery Sciences, Janssen R&D LLC, La Jolla, California, 92121, USA.<br /><searchLink fieldCode="AU" term="%22Cowman+AF%22">Cowman AF</searchLink>; Walter and Eliza Hall Institute of Medical Research, Parkville, 3052, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, 3010, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Sleebs+BE%22">Sleebs BE</searchLink>; Walter and Eliza Hall Institute of Medical Research, Parkville, 3052, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, 3010, Victoria, Australia.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101259013%22">ChemMedChem</searchLink> [ChemMedChem] 2024 Dec 16; Vol. 19 (24), pp. e202400549. <i>Date of Electronic Publication: </i>2024 Oct 29.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley-VCH%22">Wiley-VCH </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101259013 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1860-7187 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2218607179%22">18607179 </searchLink><i>NLM ISO Abbreviation: </i>ChemMedChem <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=39210733
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1002/cmdc.202400549
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: e202400549
    Titles:
      – TitleFull: Lactam Truncation Yields a Dihydroquinazolinone Scaffold with Potent Antimalarial Activity that Targets PfATP4.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Ashton TD
      – PersonEntity:
          Name:
            NameFull: Calic PPS
      – PersonEntity:
          Name:
            NameFull: Dans MG
      – PersonEntity:
          Name:
            NameFull: Kang Ooi Z
      – PersonEntity:
          Name:
            NameFull: Zhou Q
      – PersonEntity:
          Name:
            NameFull: Loi K
      – PersonEntity:
          Name:
            NameFull: Jarman KE
      – PersonEntity:
          Name:
            NameFull: Palandri J
      – PersonEntity:
          Name:
            NameFull: Qiu D
      – PersonEntity:
          Name:
            NameFull: Lehane AM
      – PersonEntity:
          Name:
            NameFull: Maity B
      – PersonEntity:
          Name:
            NameFull: De N
      – PersonEntity:
          Name:
            NameFull: Famodimu MT
      – PersonEntity:
          Name:
            NameFull: Delves MJ
      – PersonEntity:
          Name:
            NameFull: Mao EY
      – PersonEntity:
          Name:
            NameFull: Gancheva MR
      – PersonEntity:
          Name:
            NameFull: Wilson DW
      – PersonEntity:
          Name:
            NameFull: Chowdury M
      – PersonEntity:
          Name:
            NameFull: de Koning-Ward TF
      – PersonEntity:
          Name:
            NameFull: Baud D
      – PersonEntity:
          Name:
            NameFull: Brand S
      – PersonEntity:
          Name:
            NameFull: Jackson PF
      – PersonEntity:
          Name:
            NameFull: Cowman AF
      – PersonEntity:
          Name:
            NameFull: Sleebs BE
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 16
              M: 12
              Text: 2024 Dec 16
              Type: published
              Y: 2024
          Identifiers:
            – Type: issn-electronic
              Value: 1860-7187
          Numbering:
            – Type: volume
              Value: 19
            – Type: issue
              Value: 24
          Titles:
            – TitleFull: ChemMedChem
              Type: main
ResultId 1