Gene therapy for epilepsy targeting neuropeptide Y and its Y2 receptor to dentate gyrus granule cells.

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Title: Gene therapy for epilepsy targeting neuropeptide Y and its Y2 receptor to dentate gyrus granule cells.
Authors: Cattaneo S; Vita-Salute San Raffaele University, 20132, Milan, Italy.; Division of Neuroscience, IRCCS San Raffaele Scientific Institute, 20132, Milan, Italy., Bettegazzi B; Vita-Salute San Raffaele University, 20132, Milan, Italy.; Division of Neuroscience, IRCCS San Raffaele Scientific Institute, 20132, Milan, Italy., Crippa L; Vita-Salute San Raffaele University, 20132, Milan, Italy.; Division of Neuroscience, IRCCS San Raffaele Scientific Institute, 20132, Milan, Italy., Asth L; Department of Neuroscience and Rehabilitation, University of Ferrara, 44121, Ferrara, Italy., Regoni M; Vita-Salute San Raffaele University, 20132, Milan, Italy.; Division of Neuroscience, IRCCS San Raffaele Scientific Institute, 20132, Milan, Italy., Soukupova M; Department of Neuroscience and Rehabilitation, University of Ferrara, 44121, Ferrara, Italy., Zucchini S; Department of Neuroscience and Rehabilitation, University of Ferrara, 44121, Ferrara, Italy., Cantore A; Vita-Salute San Raffaele University, 20132, Milan, Italy.; San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute, 20123, Milan, Italy., Codazzi F; Vita-Salute San Raffaele University, 20132, Milan, Italy.; Division of Neuroscience, IRCCS San Raffaele Scientific Institute, 20132, Milan, Italy., Valtorta F; Vita-Salute San Raffaele University, 20132, Milan, Italy.; Division of Neuroscience, IRCCS San Raffaele Scientific Institute, 20132, Milan, Italy., Simonato M; Division of Neuroscience, IRCCS San Raffaele Scientific Institute, 20132, Milan, Italy. simonato.michele@hsr.it.; Department of Neuroscience and Rehabilitation, University of Ferrara, 44121, Ferrara, Italy. simonato.michele@hsr.it.
Source: EMBO reports [EMBO Rep] 2024 Oct; Vol. 25 (10), pp. 4387-4409. Date of Electronic Publication: 2024 Sep 09.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1469-3178
DOI:10.1038/s44319-024-00244-0