Mirtazapine to alleviate severe breathlessness in patients with COPD or interstitial lung diseases (BETTER-B): an international, multicentre, double-blind, randomised, placebo-controlled, phase 3 mixed-method trial.
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| Title: | Mirtazapine to alleviate severe breathlessness in patients with COPD or interstitial lung diseases (BETTER-B): an international, multicentre, double-blind, randomised, placebo-controlled, phase 3 mixed-method trial. |
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| Authors: | Higginson IJ; Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, London, UK; King's College Hospital NHS Foundation Trust, London, UK. Electronic address: irene.higginson@kcl.ac.uk., Brown ST; Clinical Trials Research Unit, Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, UK., Oluyase AO; Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, London, UK., May P; Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, London, UK; School of Medicine, Trinity College Dublin, Dublin, Ireland., Maddocks M; Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, London, UK., Costantini M; Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, London, UK., Bajwah S; Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, London, UK; King's College Hospital NHS Foundation Trust, London, UK., Normand C; Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, London, UK; School of Medicine, Trinity College Dublin, Dublin, Ireland., Bausewein C; LMU University Hospital, Department for Palliative Medicine, Ludwig-Maximilians-University Muenchen, Munich, Germany., Simon ST; University of Cologne, Faculty of Medicine and University Hospital, Department of Palliative Medicine and Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Cologne, Germany., Ryan K; University College Dublin and Mater Misericordiae University Hospital Dublin, Dublin, Ireland., Currow DC; Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW, Australia., Johnson MJ; Wolfson Palliative Care Research Centre, Hull York Medical School, The University of Hull, Hull, UK., Hart SP; Respiratory Research Group, Hull York Medical School, The University of Hull, Hull, UK., Mather H; Clinical Trials Research Unit, Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, UK., Krajnik M; Department of Palliative Care, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Bydgoszcz, Poland., Tanzi S; Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy., Ghirotto L; Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy., Bolton CE; NIHR Nottingham Biomedical Research Centre, Translational Medical Sciences, School of Medicine, The University of Nottingham, Nottingham, UK., Janowiak P; Division of Pulmonology, Gdanski Uniwersytet Medyczny, Gdańsk, Poland., Turola E; Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy., Jolley CJ; King's College Hospital NHS Foundation Trust, London, UK; Centre for Human & Applied Physiological Sciences, School of Basic & Medical Biosciences, King's College London, London, UK., Murden G; Clinical Trials Research Unit, Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, UK., Wilcock A; Department of Clinical Oncology, University of Nottingham and Nottingham University Hospitals NHS Trust, Nottingham, UK., Farsides B; Brighton and Sussex Medical School, University of Sussex, Brighton, UK., Brown JM; Clinical Trials Research Unit, Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, UK. |
| Corporate Authors: | BETTER-B consortium |
| Source: | The Lancet. Respiratory medicine [Lancet Respir Med] 2024 Oct; Vol. 12 (10), pp. 763-774. Date of Electronic Publication: 2024 Sep 09. |
| Publication Type: | Journal Article; Multicenter Study; Randomized Controlled Trial; Clinical Trial, Phase III; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Elsevier Country of Publication: England NLM ID: 101605555 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-2619 (Electronic) Linking ISSN: 22132600 NLM ISO Abbreviation: Lancet Respir Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 39265600 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Mirtazapine to alleviate severe breathlessness in patients with COPD or interstitial lung diseases (BETTER-B): an international, multicentre, double-blind, randomised, placebo-controlled, phase 3 mixed-method trial. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Higginson+IJ%22">Higginson IJ</searchLink>; Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, London, UK; King's College Hospital NHS Foundation Trust, London, UK. Electronic address: irene.higginson@kcl.ac.uk.<br /><searchLink fieldCode="AU" term="%22Brown+ST%22">Brown ST</searchLink>; Clinical Trials Research Unit, Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, UK.<br /><searchLink fieldCode="AU" term="%22Oluyase+AO%22">Oluyase AO</searchLink>; Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22May+P%22">May P</searchLink>; Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, London, UK; School of Medicine, Trinity College Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Maddocks+M%22">Maddocks M</searchLink>; Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Costantini+M%22">Costantini M</searchLink>; Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Bajwah+S%22">Bajwah S</searchLink>; Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, London, UK; King's College Hospital NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Normand+C%22">Normand C</searchLink>; Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, London, UK; School of Medicine, Trinity College Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Bausewein+C%22">Bausewein C</searchLink>; LMU University Hospital, Department for Palliative Medicine, Ludwig-Maximilians-University Muenchen, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Simon+ST%22">Simon ST</searchLink>; University of Cologne, Faculty of Medicine and University Hospital, Department of Palliative Medicine and Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Ryan+K%22">Ryan K</searchLink>; University College Dublin and Mater Misericordiae University Hospital Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Currow+DC%22">Currow DC</searchLink>; Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Johnson+MJ%22">Johnson MJ</searchLink>; Wolfson Palliative Care Research Centre, Hull York Medical School, The University of Hull, Hull, UK.<br /><searchLink fieldCode="AU" term="%22Hart+SP%22">Hart SP</searchLink>; Respiratory Research Group, Hull York Medical School, The University of Hull, Hull, UK.<br /><searchLink fieldCode="AU" term="%22Mather+H%22">Mather H</searchLink>; Clinical Trials Research Unit, Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, UK.<br /><searchLink fieldCode="AU" term="%22Krajnik+M%22">Krajnik M</searchLink>; Department of Palliative Care, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Bydgoszcz, Poland.<br /><searchLink fieldCode="AU" term="%22Tanzi+S%22">Tanzi S</searchLink>; Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.<br /><searchLink fieldCode="AU" term="%22Ghirotto+L%22">Ghirotto L</searchLink>; Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.<br /><searchLink fieldCode="AU" term="%22Bolton+CE%22">Bolton CE</searchLink>; NIHR Nottingham Biomedical Research Centre, Translational Medical Sciences, School of Medicine, The University of Nottingham, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Janowiak+P%22">Janowiak P</searchLink>; Division of Pulmonology, Gdanski Uniwersytet Medyczny, Gdańsk, Poland.<br /><searchLink fieldCode="AU" term="%22Turola+E%22">Turola E</searchLink>; Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.<br /><searchLink fieldCode="AU" term="%22Jolley+CJ%22">Jolley CJ</searchLink>; King's College Hospital NHS Foundation Trust, London, UK; Centre for Human & Applied Physiological Sciences, School of Basic & Medical Biosciences, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Murden+G%22">Murden G</searchLink>; Clinical Trials Research Unit, Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, UK.<br /><searchLink fieldCode="AU" term="%22Wilcock+A%22">Wilcock A</searchLink>; Department of Clinical Oncology, University of Nottingham and Nottingham University Hospitals NHS Trust, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Farsides+B%22">Farsides B</searchLink>; Brighton and Sussex Medical School, University of Sussex, Brighton, UK.<br /><searchLink fieldCode="AU" term="%22Brown+JM%22">Brown JM</searchLink>; Clinical Trials Research Unit, Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, UK. – Name: AuthorCorporate Label: Corporate Authors Group: Au Data: <searchLink fieldCode="CA" term="%22BETTER-B+consortium%22">BETTER-B consortium</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101605555%22">The Lancet. Respiratory medicine</searchLink> [Lancet Respir Med] 2024 Oct; Vol. 12 (10), pp. 763-774. <i>Date of Electronic Publication: </i>2024 Sep 09. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Multicenter Study; Randomized Controlled Trial; Clinical Trial, Phase III; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101605555 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2213-2619 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2222132600%22">22132600 </searchLink><i>NLM ISO Abbreviation: </i>Lancet Respir Med <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=39265600 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/S2213-2600(24)00187-5 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 763 Titles: – TitleFull: Mirtazapine to alleviate severe breathlessness in patients with COPD or interstitial lung diseases (BETTER-B): an international, multicentre, double-blind, randomised, placebo-controlled, phase 3 mixed-method trial. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Higginson IJ – PersonEntity: Name: NameFull: Brown ST – PersonEntity: Name: NameFull: Oluyase AO – PersonEntity: Name: NameFull: May P – PersonEntity: Name: NameFull: Maddocks M – PersonEntity: Name: NameFull: Costantini M – PersonEntity: Name: NameFull: Bajwah S – PersonEntity: Name: NameFull: Normand C – PersonEntity: Name: NameFull: Bausewein C – PersonEntity: Name: NameFull: Simon ST – PersonEntity: Name: NameFull: Ryan K – PersonEntity: Name: NameFull: Currow DC – PersonEntity: Name: NameFull: Johnson MJ – PersonEntity: Name: NameFull: Hart SP – PersonEntity: Name: NameFull: Mather H – PersonEntity: Name: NameFull: Krajnik M – PersonEntity: Name: NameFull: Tanzi S – PersonEntity: Name: NameFull: Ghirotto L – PersonEntity: Name: NameFull: Bolton CE – PersonEntity: Name: NameFull: Janowiak P – PersonEntity: Name: NameFull: Turola E – PersonEntity: Name: NameFull: Jolley CJ – PersonEntity: Name: NameFull: Murden G – PersonEntity: Name: NameFull: Wilcock A – PersonEntity: Name: NameFull: Farsides B – PersonEntity: Name: NameFull: Brown JM IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 10 Text: 2024 Oct Type: published Y: 2024 Identifiers: – Type: issn-electronic Value: 2213-2619 Numbering: – Type: volume Value: 12 – Type: issue Value: 10 Titles: – TitleFull: The Lancet. Respiratory medicine Type: main |
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