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Datopotamab-deruxtecan in early-stage breast cancer: the sequential multiple assignment randomized I-SPY2.2 phase 2 trial.

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Title: Datopotamab-deruxtecan in early-stage breast cancer: the sequential multiple assignment randomized I-SPY2.2 phase 2 trial.
Authors: Khoury K; University of Alabama at Birmingham, Birmingham, AL, USA., Meisel JL; Emory University, Atlanta, GA, USA., Yau C; University of California San Francisco, San Francisco, CA, USA., Rugo HS; University of California San Francisco, San Francisco, CA, USA., Nanda R; University of Chicago, Chicago, IL, USA., Davidian M; North Carolina State University, Raleigh, NC, USA., Tsiatis B; North Carolina State University, Raleigh, NC, USA., Chien AJ; University of California San Francisco, San Francisco, CA, USA., Wallace AM; University of California San Diego, San Diego, CA, USA., Arora M; University of California Davis, Davis, CA, USA., Rozenblit M; Yale University, New Haven, CT, USA., Hershman DL; Columbia University, New York, NY, USA., Zimmer A; Oregon Health Sciences University, Portland, OR, USA., Clark AS; University of Pennsylvania, Philadelphia, PA, USA., Beckwith H; University of Minnesota, Minneapolis, MN, USA., Elias AD; University of Colorado Denver, Denver, CO, USA., Stringer-Reasor E; University of Alabama at Birmingham, Birmingham, AL, USA., Boughey JC; The Mayo Clinic, Rochester, MN, USA., Nangia C; HOAG Family Cancer Institute, Newport Beach, CA, USA., Vaklavas C; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., Omene C; Cooperman Barnabas Medical Center, New Brunswick, NJ, USA.; Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA., Albain KS; Stritch School of Medicine, Loyola University Chicago, Chicago, IL, USA., Kalinsky KM; Emory University, Atlanta, GA, USA., Isaacs C; Lombardi Comprehensive Cancer Center, Georgetown University, Washington DC, USA., Tseng J; City of Hope Orange County Lennar Foundation Cancer Center, Orange County, CA, USA., Roussos Torres ET; University of Southern California, Los Angeles, CA, USA., Thomas B; Sparrow Health System, Lansing, MI, USA., Thomas A; Wake Forest University, Winston-Salem, NC, USA., Sanford A; Sanford Health, Sioux Falls, SD, USA., Balassanian R; University of California San Francisco, San Francisco, CA, USA., Ewing C; University of California San Francisco, San Francisco, CA, USA., Yeung K; University of California San Diego, San Diego, CA, USA., Sauder C; University of California Davis, Davis, CA, USA., Sanft T; Yale University, New Haven, CT, USA., Pusztai L; Yale University, New Haven, CT, USA., Trivedi MS; Columbia University, New York, NY, USA., Outhaythip A; Oregon Health Sciences University, Portland, OR, USA., Li W; University of California San Francisco, San Francisco, CA, USA., Onishi N; University of California San Francisco, San Francisco, CA, USA., Asare AL; University of California San Francisco, San Francisco, CA, USA.; Quantum Leap Healthcare Collaborative, San Francisco, CA, USA., Beineke P; Quantum Leap Healthcare Collaborative, San Francisco, CA, USA., Norwood P; Quantum Leap Healthcare Collaborative, San Francisco, CA, USA., Brown-Swigart L; University of California San Francisco, San Francisco, CA, USA., Hirst GL; University of California San Francisco, San Francisco, CA, USA., Matthews JB; University of California San Francisco, San Francisco, CA, USA., Moore B; Wake Forest University, Winston-Salem, NC, USA., Fraser Symmans W; University of Texas MD Anderson Cancer Center, Houston, TX, USA., Price E; University of California San Francisco, San Francisco, CA, USA., Beedle C; University of California San Francisco, San Francisco, CA, USA., Perlmutter J; The Gemini Group, Ann Arbor, MI, USA., Pohlmann P; University of Texas MD Anderson Cancer Center, Houston, TX, USA., Shatsky RA; University of California San Diego, San Diego, CA, USA., DeMichele A; University of Pennsylvania, Philadelphia, PA, USA., Yee D; University of Minnesota, Minneapolis, MN, USA., van 't Veer LJ; University of California San Francisco, San Francisco, CA, USA., Hylton NM; University of California San Francisco, San Francisco, CA, USA., Esserman LJ; University of California San Francisco, San Francisco, CA, USA. laura.esserman@ucsf.edu.
Source: Nature medicine [Nat Med] 2024 Dec; Vol. 30 (12), pp. 3728-3736. Date of Electronic Publication: 2024 Sep 14.
Publication Type: Journal Article; Clinical Trial, Phase II; Randomized Controlled Trial; Multicenter Study
Journal Info: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE
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