A humanized ACE2 mouse model recapitulating age- and sex-dependent immunopathogenesis of COVID-19.
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| Title: | A humanized ACE2 mouse model recapitulating age- and sex-dependent immunopathogenesis of COVID-19. |
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| Authors: | Park U; Department of Microbiology and Immunology, Seoul National University College of Medicine, Seoul, South Korea.; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, South Korea.; Institute of Endemic Disease, Seoul National University Medical Research Center, Seoul, South Korea., Lee JH; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, South Korea.; GEMCRO Inc., Seoul, South Korea., Kim U; Department of Systems Biology, College of Life Science and Biotechnology, Yonsei University, Seoul, South Korea., Jeon K; Department of Microbiology and Immunology, Seoul National University College of Medicine, Seoul, South Korea.; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, South Korea., Kim Y; Department of Microbiology and Immunology, Seoul National University College of Medicine, Seoul, South Korea.; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, South Korea.; Institute of Endemic Disease, Seoul National University Medical Research Center, Seoul, South Korea., Kim H; Department of Microbiology and Immunology, Seoul National University College of Medicine, Seoul, South Korea.; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, South Korea., Kang JI; Department of Microbiology and Immunology, Seoul National University College of Medicine, Seoul, South Korea.; Institute of Endemic Disease, Seoul National University Medical Research Center, Seoul, South Korea., Park MY; GEMCRO Inc., Seoul, South Korea., Park SH; GEMCRO Inc., Seoul, South Korea., Cha JS; Department of Systems Biology, College of Life Science and Biotechnology, Yonsei University, Seoul, South Korea., Yoon GY; Department of Systems Biology, College of Life Science and Biotechnology, Yonsei University, Seoul, South Korea., Jeong DE; Korea Zoonosis Research Institute, Jeonbuk National University, Iksan, Jeollabuk-do, South Korea., Kim T; Department of Microbiology and Immunology, Seoul National University College of Medicine, Seoul, South Korea.; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, South Korea., Oh S; Department of Microbiology and Immunology, Seoul National University College of Medicine, Seoul, South Korea.; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, South Korea., Yoon SH; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, South Korea.; Department of Physiology & Biomedical Sciences, Ischemic/hypoxic Disease Institute, Seoul National University College of Medicine, Seoul, South Korea., Jin L; Department of Physiology & Biomedical Sciences, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul, South Korea., Ahn Y; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, South Korea.; Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center, Seoul, South Korea., Lim MY; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, South Korea.; Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center, Seoul, South Korea., Han SR; Department of Microbiology and Immunology, Eulji University School of Medicine, Daejeon, South Korea., Kim HY; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, South Korea.; Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center, Seoul, South Korea., Kim MH; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, South Korea.; Department of Physiology & Biomedical Sciences, Ischemic/hypoxic Disease Institute, Seoul National University College of Medicine, Seoul, South Korea.; Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, South Korea., Zhang YH; Department of Physiology & Biomedical Sciences, Ischemic/hypoxic Disease Institute, Seoul National University College of Medicine, Seoul, South Korea.; Department of Physiology & Biomedical Sciences, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul, South Korea., Kang JG; Korea Zoonosis Research Institute, Jeonbuk National University, Iksan, Jeollabuk-do, South Korea., Lee MS; Department of Microbiology and Immunology, Eulji University School of Medicine, Daejeon, South Korea., Jeon YK; Department of Pathology, Seoul National University College of Medicine, Seoul, South Korea., Cho HS; Department of Systems Biology, College of Life Science and Biotechnology, Yonsei University, Seoul, South Korea., Lee HW; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, South Korea.; GEMCRO Inc., Seoul, South Korea., Cho NH; Department of Microbiology and Immunology, Seoul National University College of Medicine, Seoul, South Korea.; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, South Korea.; Institute of Endemic Disease, Seoul National University Medical Research Center, Seoul, South Korea.; Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, South Korea.; Department of Pathology, Seoul National University College of Medicine, Seoul, South Korea. |
| Source: | Journal of medical virology [J Med Virol] 2024 Sep; Vol. 96 (9), pp. e29915. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Wiley-Liss Country of Publication: United States NLM ID: 7705876 Publication Model: Print Cited Medium: Internet ISSN: 1096-9071 (Electronic) Linking ISSN: 01466615 NLM ISO Abbreviation: J Med Virol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1096-9071 |
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| DOI: | 10.1002/jmv.29915 |
