Peripherally restricted PICK1 inhibitor mPD5 ameliorates pain behaviors in murine inflammatory and neuropathic pain models.

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Title: Peripherally restricted PICK1 inhibitor mPD5 ameliorates pain behaviors in murine inflammatory and neuropathic pain models.
Authors: Jensen KL; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience., Christensen NR; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience.; Center for Biopharmaceuticals, Department of Drug Design and Pharmacology, and., Goddard CM; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience., Jager SE; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience., Noes-Holt G; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience., Kanneworff IB; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience.; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Jakobsen A; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience., Jiménez-Fernández L; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience., Peck EG; Department of Translational Neuroscience, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA., Sivertsen L; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience., Comaposada Baro R; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience., Houser GA; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience., Mayer FP; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience., Diaz-delCastillo M; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Topp ML; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience., Hopkins C; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Thomsen CD; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Soltan ABI; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Tidemand FG; X-ray and Neutron Science, Niels Bohr Institute, Faculty of Science, University of Copenhagen, Copenhagen, Denmark., Arleth L; X-ray and Neutron Science, Niels Bohr Institute, Faculty of Science, University of Copenhagen, Copenhagen, Denmark., Heegaard AM; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Sørensen AT; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience., Madsen KL; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience.
Source: JCI insight [JCI Insight] 2024 Sep 17; Vol. 9 (20). Date of Electronic Publication: 2024 Sep 17.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Electronic Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2379-3708
DOI:10.1172/jci.insight.170976