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Peripherally restricted PICK1 inhibitor mPD5 ameliorates pain behaviors in murine inflammatory and neuropathic pain models.

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Title: Peripherally restricted PICK1 inhibitor mPD5 ameliorates pain behaviors in murine inflammatory and neuropathic pain models.
Authors: Jensen KL; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience., Christensen NR; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience.; Center for Biopharmaceuticals, Department of Drug Design and Pharmacology, and., Goddard CM; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience., Jager SE; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience., Noes-Holt G; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience., Kanneworff IB; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience.; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Jakobsen A; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience., Jiménez-Fernández L; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience., Peck EG; Department of Translational Neuroscience, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA., Sivertsen L; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience., Comaposada Baro R; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience., Houser GA; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience., Mayer FP; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience., Diaz-delCastillo M; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Topp ML; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience., Hopkins C; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Thomsen CD; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Soltan ABI; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Tidemand FG; X-ray and Neutron Science, Niels Bohr Institute, Faculty of Science, University of Copenhagen, Copenhagen, Denmark., Arleth L; X-ray and Neutron Science, Niels Bohr Institute, Faculty of Science, University of Copenhagen, Copenhagen, Denmark., Heegaard AM; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Sørensen AT; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience., Madsen KL; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience.
Source: JCI insight [JCI Insight] 2024 Sep 17; Vol. 9 (20). Date of Electronic Publication: 2024 Sep 17.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Electronic Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Peripherally restricted PICK1 inhibitor mPD5 ameliorates pain behaviors in murine inflammatory and neuropathic pain models.
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  Data: <searchLink fieldCode="AU" term="%22Jensen+KL%22">Jensen KL</searchLink>; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience.<br /><searchLink fieldCode="AU" term="%22Christensen+NR%22">Christensen NR</searchLink>; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience.; Center for Biopharmaceuticals, Department of Drug Design and Pharmacology, and.<br /><searchLink fieldCode="AU" term="%22Goddard+CM%22">Goddard CM</searchLink>; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience.<br /><searchLink fieldCode="AU" term="%22Jager+SE%22">Jager SE</searchLink>; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience.<br /><searchLink fieldCode="AU" term="%22Noes-Holt+G%22">Noes-Holt G</searchLink>; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience.<br /><searchLink fieldCode="AU" term="%22Kanneworff+IB%22">Kanneworff IB</searchLink>; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience.; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Jakobsen+A%22">Jakobsen A</searchLink>; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience.<br /><searchLink fieldCode="AU" term="%22Jiménez-Fernández+L%22">Jiménez-Fernández L</searchLink>; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience.<br /><searchLink fieldCode="AU" term="%22Peck+EG%22">Peck EG</searchLink>; Department of Translational Neuroscience, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Sivertsen+L%22">Sivertsen L</searchLink>; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience.<br /><searchLink fieldCode="AU" term="%22Comaposada+Baro+R%22">Comaposada Baro R</searchLink>; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience.<br /><searchLink fieldCode="AU" term="%22Houser+GA%22">Houser GA</searchLink>; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience.<br /><searchLink fieldCode="AU" term="%22Mayer+FP%22">Mayer FP</searchLink>; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience.<br /><searchLink fieldCode="AU" term="%22Diaz-delCastillo+M%22">Diaz-delCastillo M</searchLink>; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Topp+ML%22">Topp ML</searchLink>; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience.<br /><searchLink fieldCode="AU" term="%22Hopkins+C%22">Hopkins C</searchLink>; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Thomsen+CD%22">Thomsen CD</searchLink>; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Soltan+ABI%22">Soltan ABI</searchLink>; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Tidemand+FG%22">Tidemand FG</searchLink>; X-ray and Neutron Science, Niels Bohr Institute, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Arleth+L%22">Arleth L</searchLink>; X-ray and Neutron Science, Niels Bohr Institute, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Heegaard+AM%22">Heegaard AM</searchLink>; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Sørensen+AT%22">Sørensen AT</searchLink>; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience.<br /><searchLink fieldCode="AU" term="%22Madsen+KL%22">Madsen KL</searchLink>; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience.
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  Data: <searchLink fieldCode="JN" term="%22101676073%22">JCI insight</searchLink> [JCI Insight] 2024 Sep 17; Vol. 9 (20). <i>Date of Electronic Publication: </i>2024 Sep 17.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+for+Clinical+Investigation%22">American Society for Clinical Investigation </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101676073 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2379-3708 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223793708%22">23793708 </searchLink><i>NLM ISO Abbreviation: </i>JCI Insight <i>Subsets: </i>MEDLINE
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