A polarized FGF8 source specifies frontotemporal signatures in spatially oriented cell populations of cortical assembloids.

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Title: A polarized FGF8 source specifies frontotemporal signatures in spatially oriented cell populations of cortical assembloids.
Authors: Bosone C; Institute of Molecular Biotechnology of the Austrian Academy of Science (IMBA), Vienna BioCenter (VBC), Vienna, Austria., Castaldi D; Human Technopole, Milan, Italy.; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy., Burkard TR; Institute of Molecular Biotechnology of the Austrian Academy of Science (IMBA), Vienna BioCenter (VBC), Vienna, Austria., Guzman SJ; Institute of Molecular Biotechnology of the Austrian Academy of Science (IMBA), Vienna BioCenter (VBC), Vienna, Austria., Wyatt T; Laboratoire 'Matière et Systèmes Complexes' (MSC), UMR 7057 CNRS, University of Paris, Paris, France., Cheroni C; Human Technopole, Milan, Italy., Caporale N; Human Technopole, Milan, Italy.; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy., Bajaj S; Institute of Molecular Biotechnology of the Austrian Academy of Science (IMBA), Vienna BioCenter (VBC), Vienna, Austria.; Department of Neurology, The University of Texas Health Science Center at Houston, McGovern Medical School, Houston, TX, USA., Bagley JA; Institute of Molecular Biotechnology of the Austrian Academy of Science (IMBA), Vienna BioCenter (VBC), Vienna, Austria., Li C; Institute of Molecular Biotechnology of the Austrian Academy of Science (IMBA), Vienna BioCenter (VBC), Vienna, Austria., Sorre B; Laboratoire 'Matière et Systèmes Complexes' (MSC), UMR 7057 CNRS, University of Paris, Paris, France.; Physics of Cells and Cancer, Institut Curie, Université PSL, Sorbonne University, CNRS UMR168, Paris, France., Villa CE; Human Technopole, Milan, Italy., Testa G; Human Technopole, Milan, Italy. giuseppe.testa@fht.org.; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy. giuseppe.testa@fht.org., Krenn V; Institute of Molecular Biotechnology of the Austrian Academy of Science (IMBA), Vienna BioCenter (VBC), Vienna, Austria. veronica.krenn@unimib.it.; Department of Biotechnology and Bioscience, University of Milan-Bicocca, Milan, Italy. veronica.krenn@unimib.it., Knoblich JA; Institute of Molecular Biotechnology of the Austrian Academy of Science (IMBA), Vienna BioCenter (VBC), Vienna, Austria. juergen.knoblich@imba.oeaw.ac.at.; Department of Neurology, Medical University of Vienna, Vienna, Austria. juergen.knoblich@imba.oeaw.ac.at.
Source: Nature methods [Nat Methods] 2024 Nov; Vol. 21 (11), pp. 2147-2159. Date of Electronic Publication: 2024 Sep 18.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101215604 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1548-7105 (Electronic) Linking ISSN: 15487091 NLM ISO Abbreviation: Nat Methods Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1548-7105
DOI:10.1038/s41592-024-02412-5