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Ceramide synthesis inhibitors prevent lipid-induced insulin resistance through the DAG-PKCε-insulin receptorT1150 phosphorylation pathway.

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Title: Ceramide synthesis inhibitors prevent lipid-induced insulin resistance through the DAG-PKCε-insulin receptorT1150 phosphorylation pathway.
Authors: Xu W; Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06510, USA; Department of Endocrinology, The First Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, Zhejiang 310003, China., Zhang D; Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06510, USA., Ma Y; Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06510, USA; Department of Endocrinology, The Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, Jiangsu 225009, China., Gaspar RC; Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06510, USA., Kahn M; Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06510, USA., Nasiri A; Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06510, USA., Murray S; Ionis Pharmaceuticals, Carlsbad, CA 92010, USA., Samuel VT; Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06510, USA; VA Connecticut Healthcare System, West Haven, CT 06516, USA. Electronic address: varman.samuel@yale.edu., Shulman GI; Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06510, USA; Department of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, CT 06510, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address: gerald.shulman@yale.edu.
Source: Cell reports [Cell Rep] 2024 Oct 22; Vol. 43 (10), pp. 114746. Date of Electronic Publication: 2024 Sep 19.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Ceramide synthesis inhibitors prevent lipid-induced insulin resistance through the DAG-PKCε-insulin receptor<superscript>T1150</superscript> phosphorylation pathway.
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  Data: <searchLink fieldCode="AU" term="%22Xu+W%22">Xu W</searchLink>; Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06510, USA; Department of Endocrinology, The First Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, Zhejiang 310003, China.<br /><searchLink fieldCode="AU" term="%22Zhang+D%22">Zhang D</searchLink>; Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06510, USA.<br /><searchLink fieldCode="AU" term="%22Ma+Y%22">Ma Y</searchLink>; Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06510, USA; Department of Endocrinology, The Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, Jiangsu 225009, China.<br /><searchLink fieldCode="AU" term="%22Gaspar+RC%22">Gaspar RC</searchLink>; Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06510, USA.<br /><searchLink fieldCode="AU" term="%22Kahn+M%22">Kahn M</searchLink>; Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06510, USA.<br /><searchLink fieldCode="AU" term="%22Nasiri+A%22">Nasiri A</searchLink>; Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06510, USA.<br /><searchLink fieldCode="AU" term="%22Murray+S%22">Murray S</searchLink>; Ionis Pharmaceuticals, Carlsbad, CA 92010, USA.<br /><searchLink fieldCode="AU" term="%22Samuel+VT%22">Samuel VT</searchLink>; Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06510, USA; VA Connecticut Healthcare System, West Haven, CT 06516, USA. Electronic address: varman.samuel@yale.edu.<br /><searchLink fieldCode="AU" term="%22Shulman+GI%22">Shulman GI</searchLink>; Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06510, USA; Department of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, CT 06510, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address: gerald.shulman@yale.edu.
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  Data: <searchLink fieldCode="JN" term="%22101573691%22">Cell reports</searchLink> [Cell Rep] 2024 Oct 22; Vol. 43 (10), pp. 114746. <i>Date of Electronic Publication: </i>2024 Sep 19.
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  Data: Journal Article; Research Support, N.I.H., Extramural
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101573691 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2211-1247 (Electronic) <i>NLM ISO Abbreviation: </i>Cell Rep <i>Subsets: </i>MEDLINE
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