FcRn-enhancing mutations lead to increased and prolonged levels of the HIV CCR5-blocking monoclonal antibody leronlimab in the fetuses and newborns of pregnant rhesus macaques.
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| Title: | FcRn-enhancing mutations lead to increased and prolonged levels of the HIV CCR5-blocking monoclonal antibody leronlimab in the fetuses and newborns of pregnant rhesus macaques. |
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| Authors: | Zikos J; Nonhuman Primate Reagent Resource (NHPRR), Department of Medicine - Innate Immunity, UMass Chan Medical School, Worcester, MA, USA., Webb GM; Division of Pathobiology & Immunology, Oregon National Primate Research Center, Oregon Health & Science University, Portland, OR, USA., Wu HL; Division of Pathobiology & Immunology, Oregon National Primate Research Center, Oregon Health & Science University, Portland, OR, USA., Reed JS; Division of Pathobiology & Immunology, Oregon National Primate Research Center, Oregon Health & Science University, Portland, OR, USA., Watanabe J; California National Primate Research Center (CNPRC), University of California, Davis, CA, USA., Usachenko JL; California National Primate Research Center (CNPRC), University of California, Davis, CA, USA., Shaqra AM; Department of Biochemistry and Molecular Biotechnology, UMass Chan Medical School, Worcester, MA, USA., Schiffer CA; Department of Biochemistry and Molecular Biotechnology, UMass Chan Medical School, Worcester, MA, USA., Van Rompay KKA; California National Primate Research Center (CNPRC), University of California, Davis, CA, USA.; Department of Pathology, Microbiology and Immunology, University of California, Davis, CA, USA., Sacha JB; Division of Pathobiology & Immunology, Oregon National Primate Research Center, Oregon Health & Science University, Portland, OR, USA., Magnani DM; Nonhuman Primate Reagent Resource (NHPRR), Department of Medicine - Innate Immunity, UMass Chan Medical School, Worcester, MA, USA. |
| Source: | MAbs [MAbs] 2024 Jan-Dec; Vol. 16 (1), pp. 2406788. Date of Electronic Publication: 2024 Sep 26. |
| Publication Type: | Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101479829 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1942-0870 (Electronic) Linking ISSN: 19420862 NLM ISO Abbreviation: MAbs Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1942-0870 |
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| DOI: | 10.1080/19420862.2024.2406788 |
