Optimizing the detection of N-nitrosamine mutagenicity in the Ames test.

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Title: Optimizing the detection of N-nitrosamine mutagenicity in the Ames test.
Authors: Heflich RH; U.S. Food and Drug Administration, National Center for Toxicological Research, USA. Electronic address: robert.heflich@fda.hhs.gov., Bishop ME; U.S. Food and Drug Administration, National Center for Toxicological Research, USA., Mittelstaedt RA; U.S. Food and Drug Administration, National Center for Toxicological Research, USA., Yan J; U.S. Food and Drug Administration, National Center for Toxicological Research, USA., Guerrero SK; U.S. Food and Drug Administration, National Center for Toxicological Research, USA., Sims AM; U.S. Food and Drug Administration, National Center for Toxicological Research, USA., Mitchell K; U.S. Food and Drug Administration, National Center for Toxicological Research, USA., Moore N; U.S. Food and Drug Administration, National Center for Toxicological Research, USA., Li X; U.S. Food and Drug Administration, National Center for Toxicological Research, USA., Mei N; U.S. Food and Drug Administration, National Center for Toxicological Research, USA., Elespuru RK; U.S Food and Drug Administration, USA., King ST; U.S. Food and Drug Administration, Center for Drug Evaluation and Research, Office of Generic Drugs, USA., Keire DA; U.S. Food and Drug Administration, Center for Drug Evaluation and Research, Office of Pharmaceutical Quality, USA., Kruhlak NL; U.S. Food and Drug Administration, Center for Drug Evaluation and Research, Office of Translational Sciences, USA., Dorsam RT; U.S. Food and Drug Administration, Center for Drug Evaluation and Research, Office of Generic Drugs, USA., Raw AS; U.S. Food and Drug Administration, Center for Drug Evaluation and Research, Office of Pharmaceutical Quality, USA., Davis Bruno KL; U.S. Food and Drug Administration, Center for Drug Evaluation and Research, Office of New Drugs, USA., McGovern TJ; U.S. Food and Drug Administration, Center for Drug Evaluation and Research, Office of New Drugs, USA., Atrakchi AH; U.S. Food and Drug Administration, Center for Drug Evaluation and Research, Office of New Drugs, USA.
Source: Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2024 Nov; Vol. 153, pp. 105709. Date of Electronic Publication: 2024 Sep 28.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8214983 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0295 (Electronic) Linking ISSN: 02732300 NLM ISO Abbreviation: Regul Toxicol Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1096-0295
DOI:10.1016/j.yrtph.2024.105709