An iron-rich subset of macrophages promotes tumor growth through a Bach1-Ednrb axis.

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Title: An iron-rich subset of macrophages promotes tumor growth through a Bach1-Ednrb axis.
Authors: Folkert IW; Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA.; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA.; Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Molina Arocho WA; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA.; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., To TKJ; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA.; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Devalaraja S; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA.; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Molina IS; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA.; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Shoush J; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA.; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Mohei H; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA.; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Zhai L; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Akhtar MN; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Kochat V; Department of Genomic Medicine and MDACC Epigenomics Therapy Initiative, MD Anderson Cancer Center, Houston, TX, USA., Arslan E; Department of Genomic Medicine and MDACC Epigenomics Therapy Initiative, MD Anderson Cancer Center, Houston, TX, USA., Lazar AJ; Department of Genomic Medicine and MDACC Epigenomics Therapy Initiative, MD Anderson Cancer Center, Houston, TX, USA.; Department of Anatomical Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Wani K; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Israel WP; Department of Genomic Medicine and MDACC Epigenomics Therapy Initiative, MD Anderson Cancer Center, Houston, TX, USA., Zhang Z; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA., Chaluvadi VS; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Norgard RJ; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Liu Y; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Fuller AM; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Dang MT; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Division of Neurology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Neurology, Washington University in St. Louis Schoold of Medicine, St. Louis, MO, USA., Roses RE; Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Karakousis GC; Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Miura JT; Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Fraker DL; Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Eisinger-Mathason TSK; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Simon MC; Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA.; Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Weber K; Department of Orthopedic Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Tan K; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Fan Y; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Rai K; Department of Genomic Medicine and MDACC Epigenomics Therapy Initiative, MD Anderson Cancer Center, Houston, TX, USA., Haldar M; Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA.; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA.; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Source: The Journal of experimental medicine [J Exp Med] 2024 Oct 07; Vol. 221 (10). Date of Electronic Publication: 2024 Sep 30.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 2985109R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-9538 (Electronic) Linking ISSN: 00221007 NLM ISO Abbreviation: J Exp Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1540-9538
DOI:10.1084/jem.20230420