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An iron-rich subset of macrophages promotes tumor growth through a Bach1-Ednrb axis.

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Title: An iron-rich subset of macrophages promotes tumor growth through a Bach1-Ednrb axis.
Authors: Folkert IW; Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA.; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA.; Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Molina Arocho WA; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA.; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., To TKJ; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA.; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Devalaraja S; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA.; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Molina IS; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA.; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Shoush J; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA.; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Mohei H; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA.; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Zhai L; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Akhtar MN; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Kochat V; Department of Genomic Medicine and MDACC Epigenomics Therapy Initiative, MD Anderson Cancer Center, Houston, TX, USA., Arslan E; Department of Genomic Medicine and MDACC Epigenomics Therapy Initiative, MD Anderson Cancer Center, Houston, TX, USA., Lazar AJ; Department of Genomic Medicine and MDACC Epigenomics Therapy Initiative, MD Anderson Cancer Center, Houston, TX, USA.; Department of Anatomical Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Wani K; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Israel WP; Department of Genomic Medicine and MDACC Epigenomics Therapy Initiative, MD Anderson Cancer Center, Houston, TX, USA., Zhang Z; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA., Chaluvadi VS; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Norgard RJ; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Liu Y; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Fuller AM; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Dang MT; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Division of Neurology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Neurology, Washington University in St. Louis Schoold of Medicine, St. Louis, MO, USA., Roses RE; Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Karakousis GC; Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Miura JT; Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Fraker DL; Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Eisinger-Mathason TSK; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Simon MC; Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA.; Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Weber K; Department of Orthopedic Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Tan K; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Fan Y; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Rai K; Department of Genomic Medicine and MDACC Epigenomics Therapy Initiative, MD Anderson Cancer Center, Houston, TX, USA., Haldar M; Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA.; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA.; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Source: The Journal of experimental medicine [J Exp Med] 2024 Oct 07; Vol. 221 (10). Date of Electronic Publication: 2024 Sep 30.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 2985109R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-9538 (Electronic) Linking ISSN: 00221007 NLM ISO Abbreviation: J Exp Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: An iron-rich subset of macrophages promotes tumor growth through a Bach1-Ednrb axis.
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  Data: <searchLink fieldCode="AU" term="%22Folkert+IW%22">Folkert IW</searchLink>; Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA.; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA.; Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Molina+Arocho+WA%22">Molina Arocho WA</searchLink>; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA.; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22To+TKJ%22">To TKJ</searchLink>; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA.; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Devalaraja+S%22">Devalaraja S</searchLink>; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA.; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Molina+IS%22">Molina IS</searchLink>; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA.; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Shoush+J%22">Shoush J</searchLink>; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA.; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Mohei+H%22">Mohei H</searchLink>; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA.; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Zhai+L%22">Zhai L</searchLink>; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Akhtar+MN%22">Akhtar MN</searchLink>; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Kochat+V%22">Kochat V</searchLink>; Department of Genomic Medicine and MDACC Epigenomics Therapy Initiative, MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Arslan+E%22">Arslan E</searchLink>; Department of Genomic Medicine and MDACC Epigenomics Therapy Initiative, MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Lazar+AJ%22">Lazar AJ</searchLink>; Department of Genomic Medicine and MDACC Epigenomics Therapy Initiative, MD Anderson Cancer Center, Houston, TX, USA.; Department of Anatomical Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Wani+K%22">Wani K</searchLink>; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Israel+WP%22">Israel WP</searchLink>; Department of Genomic Medicine and MDACC Epigenomics Therapy Initiative, MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+Z%22">Zhang Z</searchLink>; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Chaluvadi+VS%22">Chaluvadi VS</searchLink>; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Norgard+RJ%22">Norgard RJ</searchLink>; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Fuller+AM%22">Fuller AM</searchLink>; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Dang+MT%22">Dang MT</searchLink>; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Division of Neurology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Neurology, Washington University in St. Louis Schoold of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Roses+RE%22">Roses RE</searchLink>; Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Karakousis+GC%22">Karakousis GC</searchLink>; Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Miura+JT%22">Miura JT</searchLink>; Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Fraker+DL%22">Fraker DL</searchLink>; Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Eisinger-Mathason+TSK%22">Eisinger-Mathason TSK</searchLink>; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Simon+MC%22">Simon MC</searchLink>; Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA.; Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Weber+K%22">Weber K</searchLink>; Department of Orthopedic Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Tan+K%22">Tan K</searchLink>; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Fan+Y%22">Fan Y</searchLink>; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Rai+K%22">Rai K</searchLink>; Department of Genomic Medicine and MDACC Epigenomics Therapy Initiative, MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Haldar+M%22">Haldar M</searchLink>; Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA.; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA.; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
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  Data: <searchLink fieldCode="JN" term="%222985109R%22">The Journal of experimental medicine</searchLink> [J Exp Med] 2024 Oct 07; Vol. 221 (10). <i>Date of Electronic Publication: </i>2024 Sep 30.
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