Proapoptotic activity of JNK-sensitive BH3-only proteins underpins ovarian cancer response to replication checkpoint inhibitors.

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Title: Proapoptotic activity of JNK-sensitive BH3-only proteins underpins ovarian cancer response to replication checkpoint inhibitors.
Authors: Venkatachalam A; Department of Molecular Pharmacology & Experimental Therapeutics, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA.; Department of Oncology, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA., Correia C; Department of Oncology, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA., Peterson KL; Department of Oncology, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA., Hou X; Department of Oncology, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA., Schneider PA; Department of Oncology, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA., Strathman AR; Department of Oncology, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA., Flatten KS; Department of Oncology, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA., Sine CC; Department of Oncology, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA., Balczewski EA; Department of Oncology, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA.; Present Address: Department of Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor, MI, 48109, USA., McGehee CD; Department of Molecular Pharmacology & Experimental Therapeutics, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA., Larson MC; Division of Clinical Trials and Biostatistics, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA., Duffield LN; Department of Oncology, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA., Meng XW; Department of Oncology, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA., Vincelette ND; Department of Molecular Pharmacology & Experimental Therapeutics, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA.; Present Address: H. Lee Moffitt Cancer Center, Tampa, FL, 33612, USA., Ding H; Department of Oncology, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA., Oberg AL; Division of Computational Biology, Department of Quantitative Health Sciences, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA., Couch FJ; Division of Experimental Pathology, Department of Laboratory Medicine, and Pathology, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA., Swisher EM; Department of Obstetrics and Gynecology, University of Washington, 1959 NE Pacific Street, Seattle, WA, 98195, USA., Li H; Department of Molecular Pharmacology & Experimental Therapeutics, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA., Weroha SJ; Department of Molecular Pharmacology & Experimental Therapeutics, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA.; Department of Oncology, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA., Kaufmann SH; Department of Molecular Pharmacology & Experimental Therapeutics, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA. Kaufmann.Scott@Mayo.edu.; Department of Oncology, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA. Kaufmann.Scott@Mayo.edu.; Division of Hematology, Department of Medicine, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA. Kaufmann.Scott@Mayo.edu.
Source: Molecular cancer [Mol Cancer] 2024 Oct 07; Vol. 23 (1), pp. 224. Date of Electronic Publication: 2024 Oct 07.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101147698 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-4598 (Electronic) Linking ISSN: 14764598 NLM ISO Abbreviation: Mol Cancer Subsets: MEDLINE
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  Data: Proapoptotic activity of JNK-sensitive BH3-only proteins underpins ovarian cancer response to replication checkpoint inhibitors.
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  Data: <searchLink fieldCode="AU" term="%22Venkatachalam+A%22">Venkatachalam A</searchLink>; Department of Molecular Pharmacology & Experimental Therapeutics, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA.; Department of Oncology, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Correia+C%22">Correia C</searchLink>; Department of Oncology, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Peterson+KL%22">Peterson KL</searchLink>; Department of Oncology, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Hou+X%22">Hou X</searchLink>; Department of Oncology, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Schneider+PA%22">Schneider PA</searchLink>; Department of Oncology, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Strathman+AR%22">Strathman AR</searchLink>; Department of Oncology, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Flatten+KS%22">Flatten KS</searchLink>; Department of Oncology, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Sine+CC%22">Sine CC</searchLink>; Department of Oncology, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Balczewski+EA%22">Balczewski EA</searchLink>; Department of Oncology, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA.; Present Address: Department of Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor, MI, 48109, USA.<br /><searchLink fieldCode="AU" term="%22McGehee+CD%22">McGehee CD</searchLink>; Department of Molecular Pharmacology & Experimental Therapeutics, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Larson+MC%22">Larson MC</searchLink>; Division of Clinical Trials and Biostatistics, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Duffield+LN%22">Duffield LN</searchLink>; Department of Oncology, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Meng+XW%22">Meng XW</searchLink>; Department of Oncology, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Vincelette+ND%22">Vincelette ND</searchLink>; Department of Molecular Pharmacology & Experimental Therapeutics, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA.; Present Address: H. Lee Moffitt Cancer Center, Tampa, FL, 33612, USA.<br /><searchLink fieldCode="AU" term="%22Ding+H%22">Ding H</searchLink>; Department of Oncology, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Oberg+AL%22">Oberg AL</searchLink>; Division of Computational Biology, Department of Quantitative Health Sciences, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Couch+FJ%22">Couch FJ</searchLink>; Division of Experimental Pathology, Department of Laboratory Medicine, and Pathology, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Swisher+EM%22">Swisher EM</searchLink>; Department of Obstetrics and Gynecology, University of Washington, 1959 NE Pacific Street, Seattle, WA, 98195, USA.<br /><searchLink fieldCode="AU" term="%22Li+H%22">Li H</searchLink>; Department of Molecular Pharmacology & Experimental Therapeutics, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Weroha+SJ%22">Weroha SJ</searchLink>; Department of Molecular Pharmacology & Experimental Therapeutics, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA.; Department of Oncology, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Kaufmann+SH%22">Kaufmann SH</searchLink>; Department of Molecular Pharmacology & Experimental Therapeutics, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA. Kaufmann.Scott@Mayo.edu.; Department of Oncology, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA. Kaufmann.Scott@Mayo.edu.; Division of Hematology, Department of Medicine, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA. Kaufmann.Scott@Mayo.edu.
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  Data: <searchLink fieldCode="JN" term="%22101147698%22">Molecular cancer</searchLink> [Mol Cancer] 2024 Oct 07; Vol. 23 (1), pp. 224. <i>Date of Electronic Publication: </i>2024 Oct 07.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101147698 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-4598 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214764598%22">14764598 </searchLink><i>NLM ISO Abbreviation: </i>Mol Cancer <i>Subsets: </i>MEDLINE
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