Nuclear DUX4 immunohistochemistry is a highly sensitive and specific marker for the presence of CIC::DUX4 fusion in CIC-rearranged sarcomas: a study of 48 molecularly confirmed cases.

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Title: Nuclear DUX4 immunohistochemistry is a highly sensitive and specific marker for the presence of CIC::DUX4 fusion in CIC-rearranged sarcomas: a study of 48 molecularly confirmed cases.
Authors: Macedo RT; Department of Pathology and Laboratory Medicine, Diagnostic Institute, Cleveland Clinic, Cleveland, OH, USA., Baranovska-Andrigo V; Department of Pathology, Charles University, Faculty of Medicine in Pilsen, Pilsen, Czech Republic., Pancsa T; Department of Pathology, Charles University, Faculty of Medicine in Pilsen, Pilsen, Czech Republic.; Biopticka laborator Ltd, Pilsen, Czech Republic., Klubíčková N; Department of Pathology, Charles University, Faculty of Medicine in Pilsen, Pilsen, Czech Republic.; Biopticka laborator Ltd, Pilsen, Czech Republic., Rubin BP; Department of Pathology and Laboratory Medicine, Diagnostic Institute, Cleveland Clinic, Cleveland, OH, USA., Kilpatrick SE; Department of Pathology and Laboratory Medicine, Diagnostic Institute, Cleveland Clinic, Cleveland, OH, USA., Goldblum JR; Department of Pathology and Laboratory Medicine, Diagnostic Institute, Cleveland Clinic, Cleveland, OH, USA., Fritchie KJ; Department of Pathology and Laboratory Medicine, Diagnostic Institute, Cleveland Clinic, Cleveland, OH, USA., Billings SD; Department of Pathology and Laboratory Medicine, Diagnostic Institute, Cleveland Clinic, Cleveland, OH, USA., Michal M; Department of Pathology, Charles University, Faculty of Medicine in Pilsen, Pilsen, Czech Republic.; Biopticka laborator Ltd, Pilsen, Czech Republic., Švajdler M; Department of Pathology, Charles University, Faculty of Medicine in Pilsen, Pilsen, Czech Republic.; Biopticka laborator Ltd, Pilsen, Czech Republic., Kinkor Z; Biopticka laborator Ltd, Pilsen, Czech Republic., Michal M; Department of Pathology, Charles University, Faculty of Medicine in Pilsen, Pilsen, Czech Republic.; Biopticka laborator Ltd, Pilsen, Czech Republic., Dermawan JK; Department of Pathology and Laboratory Medicine, Diagnostic Institute, Cleveland Clinic, Cleveland, OH, USA.
Source: Histopathology [Histopathology] 2025 Feb; Vol. 86 (3), pp. 423-432. Date of Electronic Publication: 2024 Oct 09.
Publication Type: Journal Article
Journal Info: Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 7704136 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2559 (Electronic) Linking ISSN: 03090167 NLM ISO Abbreviation: Histopathology Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1365-2559
DOI:10.1111/his.15341