Decreased mitochondrial creatine kinase 2 impairs skeletal muscle mitochondrial function independently of insulin in type 2 diabetes.

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Title: Decreased mitochondrial creatine kinase 2 impairs skeletal muscle mitochondrial function independently of insulin in type 2 diabetes.
Authors: Rizo-Roca D; Department of Physiology and Pharmacology, Karolinska Institutet, SE-171 77 Stockholm, Sweden., Guimarães DSPSF; Department of Physiology and Pharmacology, Karolinska Institutet, SE-171 77 Stockholm, Sweden., Pendergrast LA; Department of Molecular Medicine and Surgery, Karolinska Institutet, SE-171 77 Stockholm, Sweden., Di Leo N; Department of Physiology and Pharmacology, Karolinska Institutet, SE-171 77 Stockholm, Sweden., Chibalin AV; Department of Molecular Medicine and Surgery, Karolinska Institutet, SE-171 77 Stockholm, Sweden., Maqdasy S; Department of Medicine (H7), Karolinska Institutet, Karolinska University Hospital Huddinge, SE-141 86 Stockholm, Sweden., Rydén M; Department of Medicine (H7), Karolinska Institutet, Karolinska University Hospital Huddinge, SE-141 86 Stockholm, Sweden., Näslund E; Division of Surgery, Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, SE-182 57 Danderyd, Stockholm, Sweden., Zierath JR; Department of Physiology and Pharmacology, Karolinska Institutet, SE-171 77 Stockholm, Sweden.; Department of Molecular Medicine and Surgery, Karolinska Institutet, SE-171 77 Stockholm, Sweden., Krook A; Department of Physiology and Pharmacology, Karolinska Institutet, SE-171 77 Stockholm, Sweden.
Source: Science translational medicine [Sci Transl Med] 2024 Oct 09; Vol. 16 (768), pp. eado3022. Date of Electronic Publication: 2024 Oct 09.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1946-6242
DOI:10.1126/scitranslmed.ado3022