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Transglutaminase 2 promotes epithelial-to-mesenchymal transition by regulating the expression of matrix metalloproteinase 7 in colorectal cancer cells via the MEK/ERK signaling pathway.

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Title: Transglutaminase 2 promotes epithelial-to-mesenchymal transition by regulating the expression of matrix metalloproteinase 7 in colorectal cancer cells via the MEK/ERK signaling pathway.
Authors: Blaheta RA; University Medical Center Mainz, Dept. of Urology and Pediatric Urology, 55131 Mainz, Germany. Electronic address: roman.blaheta@unimedizin-mainz.de., Han J; Department for General, Visceral, Transplant and Thoracic Surgery, Goethe University, 60590 Frankfurt am Main, Germany., Oppermann E; Department for General, Visceral, Transplant and Thoracic Surgery, Goethe University, 60590 Frankfurt am Main, Germany., Bechstein WO; Department for General, Visceral, Transplant and Thoracic Surgery, Goethe University, 60590 Frankfurt am Main, Germany., Burkhard K; Department for General, Visceral, Transplant and Thoracic Surgery, Goethe University, 60590 Frankfurt am Main, Germany; Current affiliation: Department of Legal Medicine, University of Saarland Medical School, 66421 Homburg, Germany., Haferkamp A; University Medical Center Mainz, Dept. of Urology and Pediatric Urology, 55131 Mainz, Germany., Rieger MA; Department of Medicine II, Hematology/Oncology, Goethe University, 60590 Frankfurt am Main, Germany; Cardio-Pulmonary-Institute, 60590 Frankfurt am Main, Germany; Frankfurt Cancer Institute, 60590 Frankfurt am Main, Germany; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany., Malkomes P; Department for General, Visceral, Transplant and Thoracic Surgery, Goethe University, 60590 Frankfurt am Main, Germany; Frankfurt Cancer Institute, 60590 Frankfurt am Main, Germany; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
Source: Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2025 Jan; Vol. 1871 (1), pp. 167538. Date of Electronic Publication: 2024 Oct 09.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731730 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-260X (Electronic) Linking ISSN: 09254439 NLM ISO Abbreviation: Biochim Biophys Acta Mol Basis Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1879-260X
DOI:10.1016/j.bbadis.2024.167538