Evidence for a lipofibroblast-to-Cthrc1 + myofibroblast reversible switch during the development and resolution of lung fibrosis in young mice.

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Title: Evidence for a lipofibroblast-to-Cthrc1 + myofibroblast reversible switch during the development and resolution of lung fibrosis in young mice.
Authors: Lingampally A; The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People's Hospital, Quzhou, China.; Department of Medicine II, Internal Medicine, Pulmonary and Critical Care, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany.; Department of Medicine V, Internal Medicine, Infectious Diseases and Infection Control, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany.; Cardio-Pulmonary Institute (CPI), Giessen, Germany.; Institute for Lung Health (ILH), Giessen, Germany.; A. Lingampally and M. Truchi contributed equally., Truchi M; Université Côte d'Azur, UMR CNRS 7275 Inserm 1323, IPMC, FHU-OncoAge, IHU RespiERA, Valbonne, France.; A. Lingampally and M. Truchi contributed equally., Mauduit O; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA., Delcroix V; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA., Vasquez-Pacheco E; Department of Medicine II, Internal Medicine, Pulmonary and Critical Care, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany.; Cardio-Pulmonary Institute (CPI), Giessen, Germany.; Institute for Lung Health (ILH), Giessen, Germany., Gautier-Isola M; Université Côte d'Azur, UMR CNRS 7275 Inserm 1323, IPMC, FHU-OncoAge, IHU RespiERA, Valbonne, France., Chu X; Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, P.R. China., Khadim A; Department of Medicine V, Internal Medicine, Infectious Diseases and Infection Control, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany.; Cardio-Pulmonary Institute (CPI), Giessen, Germany.; Institute for Lung Health (ILH), Giessen, Germany., Chao CM; Cardio-Pulmonary Institute (CPI), Giessen, Germany., Zabihi M; Department of Medicine V, Internal Medicine, Infectious Diseases and Infection Control, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany.; Cardio-Pulmonary Institute (CPI), Giessen, Germany.; Institute for Lung Health (ILH), Giessen, Germany., Taghizadeh S; Department of Medicine II, Internal Medicine, Pulmonary and Critical Care, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany.; Cardio-Pulmonary Institute (CPI), Giessen, Germany.; Institute for Lung Health (ILH), Giessen, Germany., Rivetti S; Department of Medicine II, Internal Medicine, Pulmonary and Critical Care, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany.; Cardio-Pulmonary Institute (CPI), Giessen, Germany.; Institute for Lung Health (ILH), Giessen, Germany., Marega M; Department of Medicine II, Internal Medicine, Pulmonary and Critical Care, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany.; Cardio-Pulmonary Institute (CPI), Giessen, Germany.; Institute for Lung Health (ILH), Giessen, Germany., Moiseenko A; Immunology and Respiratory Department, Boehringer Ingelheim Pharma GmbH, Biberach an der Riss, Germany., Hadzic S; Department of Medicine II, Internal Medicine, Pulmonary and Critical Care, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany.; Cardio-Pulmonary Institute (CPI), Giessen, Germany.; Institute for Lung Health (ILH), Giessen, Germany., Vazquez-Armendariz AI; University of Bonn, Transdisciplinary Research Area Life and Health, Organoid Biology, Life and Medical Sciences Institute, Bonn, Germany., Herold S; Department of Medicine V, Internal Medicine, Infectious Diseases and Infection Control, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany.; Cardio-Pulmonary Institute (CPI), Giessen, Germany.; Institute for Lung Health (ILH), Giessen, Germany., Günther S; Max Planck Institute for Heart and Lung Research, W.G. Kerckhoff Institute, Bad Nauheim, Germany., Millar-Büchner P; Department of Medicine II, Internal Medicine, Pulmonary and Critical Care, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany.; Cardio-Pulmonary Institute (CPI), Giessen, Germany.; Institute for Lung Health (ILH), Giessen, Germany., Koepke J; Department of Medicine II, Internal Medicine, Pulmonary and Critical Care, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany.; Cardio-Pulmonary Institute (CPI), Giessen, Germany.; Institute for Lung Health (ILH), Giessen, Germany., Samakovlis C; Department of Medicine II, Internal Medicine, Pulmonary and Critical Care, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany.; Cardio-Pulmonary Institute (CPI), Giessen, Germany.; Institute for Lung Health (ILH), Giessen, Germany., Wilhelm J; Department of Medicine II, Internal Medicine, Pulmonary and Critical Care, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany.; Cardio-Pulmonary Institute (CPI), Giessen, Germany.; Institute for Lung Health (ILH), Giessen, Germany., Bartkuhn M; Cardio-Pulmonary Institute (CPI), Giessen, Germany.; Institute for Lung Health (ILH), Giessen, Germany., Braun T; Max Planck Institute for Heart and Lung Research, W.G. Kerckhoff Institute, Bad Nauheim, Germany., Weissmann N; Department of Medicine II, Internal Medicine, Pulmonary and Critical Care, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany.; Cardio-Pulmonary Institute (CPI), Giessen, Germany.; Institute for Lung Health (ILH), Giessen, Germany., Zhang J; The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People's Hospital, Quzhou, China., Wygrecka M; Department of Medicine II, Internal Medicine, Pulmonary and Critical Care, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany.; Cardio-Pulmonary Institute (CPI), Giessen, Germany.; Institute for Lung Health (ILH), Giessen, Germany., Makarenkova HP; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA., Günther A; Department of Medicine II, Internal Medicine, Pulmonary and Critical Care, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany.; Cardio-Pulmonary Institute (CPI), Giessen, Germany.; Institute for Lung Health (ILH), Giessen, Germany., Seeger W; Department of Medicine II, Internal Medicine, Pulmonary and Critical Care, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany.; Department of Medicine V, Internal Medicine, Infectious Diseases and Infection Control, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany.; Cardio-Pulmonary Institute (CPI), Giessen, Germany.; Institute for Lung Health (ILH), Giessen, Germany., Chen C; The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People's Hospital, Quzhou, China.; C. Chen, E. El Agha, B. Mari and S. Bellusci contributed equally to this article as lead authors and supervised the work., El Agha E; Department of Medicine V, Internal Medicine, Infectious Diseases and Infection Control, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany.; Cardio-Pulmonary Institute (CPI), Giessen, Germany.; Institute for Lung Health (ILH), Giessen, Germany.; C. Chen, E. El Agha, B. Mari and S. Bellusci contributed equally to this article as lead authors and supervised the work., Mari B; Université Côte d'Azur, UMR CNRS 7275 Inserm 1323, IPMC, FHU-OncoAge, IHU RespiERA, Valbonne, France.; C. Chen, E. El Agha, B. Mari and S. Bellusci contributed equally to this article as lead authors and supervised the work., Bellusci S; The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People's Hospital, Quzhou, China saverio.bellusci@innere.med.uni-giessen.de.; Laboratory of Extracellular Lung Matrix Remodelling, Department of Internal Medicine, Cardio-Pulmonary Institute and Institute for Lung Health, Universities of Giessen and Marburg Lung Center (UGMLC), member of The German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany.; C. Chen, E. El Agha, B. Mari and S. Bellusci contributed equally to this article as lead authors and supervised the work.
Source: The European respiratory journal [Eur Respir J] 2025 Feb 06; Vol. 65 (2). Date of Electronic Publication: 2025 Feb 06 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: European Respiratory Society Country of Publication: England NLM ID: 8803460 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1399-3003 (Electronic) Linking ISSN: 09031936 NLM ISO Abbreviation: Eur Respir J Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1399-3003
DOI:10.1183/13993003.00482-2023