Senolytics To slOw Progression of Sepsis (STOP-Sepsis) in elderly patients: Study protocol for a multicenter, randomized, adaptive allocation clinical trial.
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| Title: | Senolytics To slOw Progression of Sepsis (STOP-Sepsis) in elderly patients: Study protocol for a multicenter, randomized, adaptive allocation clinical trial. |
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| Authors: | Silva M; Division of Biostatistics and Health Data Science, School of Public Health, University of Minnesota, Minneapolis, MN, 55455, USA., Wacker DA; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, 55455, USA., Driver BE; Department of Emergency Medicine, Hennepin County Medical Center, Minneapolis, MN, 55415, USA., Staugaitis A; Department of Emergency Medicine, Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, 55414, USA., Niedernhofer LJ; Institute on the Biology of Aging and Metabolism, Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, MN, 55455, USA., Schmidt EL; Institute on the Biology of Aging and Metabolism, Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, MN, 55455, USA., Kirkland JL; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Cedars-Sinai Medical Center, West Hollywood, CA, 90069, USA., Tchkonia T; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Cedars-Sinai Medical Center, West Hollywood, CA, 90069, USA., Evans T; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Cedars-Sinai Medical Center, West Hollywood, CA, 90069, USA., Serrano CH; Division of Biostatistics and Health Data Science, School of Public Health, University of Minnesota, Minneapolis, MN, 55455, USA., Ventz S; Division of Biostatistics and Health Data Science, School of Public Health, University of Minnesota, Minneapolis, MN, 55455, USA., Koopmeiners JS; Division of Biostatistics and Health Data Science, School of Public Health, University of Minnesota, Minneapolis, MN, 55455, USA., Puskarich MA; Department of Emergency Medicine, University of Minnesota School of Medicine and Hennepin Healthcare, Minneapolis, MN, 55455, USA. mike-em@umn.edu. |
| Corporate Authors: | STOP-Sepsis Investigators |
| Source: | Trials [Trials] 2024 Oct 21; Vol. 25 (1), pp. 698. Date of Electronic Publication: 2024 Oct 21. |
| Publication Type: | Clinical Trial Protocol; Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101263253 Publication Model: Electronic Cited Medium: Internet ISSN: 1745-6215 (Electronic) Linking ISSN: 17456215 NLM ISO Abbreviation: Trials Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1745-6215 |
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| DOI: | 10.1186/s13063-024-08474-2 |
