Combined MRI, high-resolution manometry and a randomised trial of bisacodyl versus hyoscine show the significance of an enlarged colon in constipation: the RECLAIM study.

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Title: Combined MRI, high-resolution manometry and a randomised trial of bisacodyl versus hyoscine show the significance of an enlarged colon in constipation: the RECLAIM study.
Authors: Wilkinson-Smith V; School of Medicine, University of Nottingham, Nottingham, UK.; NIHR Nottingham Biomedical Research Centre, Nottingham, UK., Scott M; Academic Surgical Unit, Barts and The London School of Medicine and Dentistry, London, UK., Menys A; Motilent Ltd, London, UK., Wiklendt L; College of Medicine & Public Health, Flinders University, Adelaide, South Australia, Australia., Marciani L; Translational Medical Sciences, Nottingham Digestive Diseases Centre, University of Nottingham, Nottingham, UK.; Nottingham Digestive Diseases Centre, NIHR Nottingham Biomedical Research Centre, Nottingham, UK., Atkinson D; Centre for Medical Imaging, UCL, London, UK., Sansone S; Nottingham Digestive Diseases Centre, Nottingham University Hospitals NHS Trust, Nottingham, UK., Zdanaviciene A; Barts and the London School of Medicine and Dentistry, Queen Mary University, London, UK., Coupland C; Centre for Academic Primary Care, University of Nottingham, Nottingham, UK., Knowles CH; Blizzard Institute, Queen Mary University, London, UK., Dinning P; Gastroenterology and Surgery, Flinders Medical Center, Adelaide, South Australia, Australia., Taylor SA; Imaging Department, University College London Hospitals NHS Foundation Trust, London, UK., Gowland P; NIHR Nottingham Biomedical Research Centre, Nottingham, UK.; Sir Peter Mansfield Magnetic Resonance Centre, University of Nottingham, Nottingham, UK., Hoad CL; NIHR Nottingham Biomedical Research Centre, Nottingham, UK.; Sir Peter Mansfield Magnetic Resonance Centre, University of Nottingham, Nottingham, UK., Corsetti M; NIHR Nottingham Biomedical Research Centre, Nottingham, UK.; Nottingham Digestive Diseases Biomedical Research Unit, University of Nottingham, Nottingham, UK., Spiller RC; Nottingham Digestive Diseases Centre, NIHR Nottingham Biomedical Research Centre, Nottingham, UK robin.spiller@nottingham.ac.uk.; Translational Medical Science, University of Nottingham, Nottingham, UK.
Source: Gut [Gut] 2024 Dec 10; Vol. 74 (1), pp. 35-44. Date of Electronic Publication: 2024 Dec 10.
Publication Type: Journal Article; Randomized Controlled Trial; Comparative Study; Research Support, Non-U.S. Gov't
Journal Info: Publisher: British Medical Assn Country of Publication: England NLM ID: 2985108R Publication Model: Electronic Cited Medium: Internet ISSN: 1468-3288 (Electronic) Linking ISSN: 00175749 NLM ISO Abbreviation: Gut Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1468-3288
DOI:10.1136/gutjnl-2024-332755