Engineered AAV capsid transport mutants overcome transduction deficiencies in the aged CNS.

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Title: Engineered AAV capsid transport mutants overcome transduction deficiencies in the aged CNS.
Authors: Sandoval IM; Parkinson's Disease Research Unit, Department of Translational Neuroscience, Barrow Neurological Institute, Phoenix, AZ 85013, USA., Kelley CM; Parkinson's Disease Research Unit, Department of Translational Neuroscience, Barrow Neurological Institute, Phoenix, AZ 85013, USA., Bernal-Conde LD; Parkinson's Disease Research Unit, Department of Translational Neuroscience, Barrow Neurological Institute, Phoenix, AZ 85013, USA., Steece-Collier K; Department of Translational Neuroscience, Michigan State University College of Human Medicine, Grand Rapids, MI 49506, USA., Marmion DJ; Parkinson's Disease Research Unit, Department of Translational Neuroscience, Barrow Neurological Institute, Phoenix, AZ 85013, USA., Davidsson M; Parkinson's Disease Research Unit, Department of Translational Neuroscience, Barrow Neurological Institute, Phoenix, AZ 85013, USA., Crosson SM; Division of Cellular and Molecular Therapy, Department of Pediatrics, University of Florida, Gainesville, FL 32610, USA., Boye SL; Powell Gene Therapy Center, Department of Pediatrics, University of Florida, Gainesville, FL 32610, USA., Boye SE; Division of Cellular and Molecular Therapy, Department of Pediatrics, University of Florida, Gainesville, FL 32610, USA., Manfredsson FP; Parkinson's Disease Research Unit, Department of Translational Neuroscience, Barrow Neurological Institute, Phoenix, AZ 85013, USA.
Source: Molecular therapy. Nucleic acids [Mol Ther Nucleic Acids] 2024 Sep 12; Vol. 35 (4), pp. 102332. Date of Electronic Publication: 2024 Sep 12 (Print Publication: 2024).
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101581621 Publication Model: eCollection Cited Medium: Print ISSN: 2162-2531 (Print) Linking ISSN: 21622531 NLM ISO Abbreviation: Mol Ther Nucleic Acids Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Engineered AAV capsid transport mutants overcome transduction deficiencies in the aged CNS.
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  Data: <searchLink fieldCode="AU" term="%22Sandoval+IM%22">Sandoval IM</searchLink>; Parkinson's Disease Research Unit, Department of Translational Neuroscience, Barrow Neurological Institute, Phoenix, AZ 85013, USA.<br /><searchLink fieldCode="AU" term="%22Kelley+CM%22">Kelley CM</searchLink>; Parkinson's Disease Research Unit, Department of Translational Neuroscience, Barrow Neurological Institute, Phoenix, AZ 85013, USA.<br /><searchLink fieldCode="AU" term="%22Bernal-Conde+LD%22">Bernal-Conde LD</searchLink>; Parkinson's Disease Research Unit, Department of Translational Neuroscience, Barrow Neurological Institute, Phoenix, AZ 85013, USA.<br /><searchLink fieldCode="AU" term="%22Steece-Collier+K%22">Steece-Collier K</searchLink>; Department of Translational Neuroscience, Michigan State University College of Human Medicine, Grand Rapids, MI 49506, USA.<br /><searchLink fieldCode="AU" term="%22Marmion+DJ%22">Marmion DJ</searchLink>; Parkinson's Disease Research Unit, Department of Translational Neuroscience, Barrow Neurological Institute, Phoenix, AZ 85013, USA.<br /><searchLink fieldCode="AU" term="%22Davidsson+M%22">Davidsson M</searchLink>; Parkinson's Disease Research Unit, Department of Translational Neuroscience, Barrow Neurological Institute, Phoenix, AZ 85013, USA.<br /><searchLink fieldCode="AU" term="%22Crosson+SM%22">Crosson SM</searchLink>; Division of Cellular and Molecular Therapy, Department of Pediatrics, University of Florida, Gainesville, FL 32610, USA.<br /><searchLink fieldCode="AU" term="%22Boye+SL%22">Boye SL</searchLink>; Powell Gene Therapy Center, Department of Pediatrics, University of Florida, Gainesville, FL 32610, USA.<br /><searchLink fieldCode="AU" term="%22Boye+SE%22">Boye SE</searchLink>; Division of Cellular and Molecular Therapy, Department of Pediatrics, University of Florida, Gainesville, FL 32610, USA.<br /><searchLink fieldCode="AU" term="%22Manfredsson+FP%22">Manfredsson FP</searchLink>; Parkinson's Disease Research Unit, Department of Translational Neuroscience, Barrow Neurological Institute, Phoenix, AZ 85013, USA.
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  Data: <searchLink fieldCode="JN" term="%22101581621%22">Molecular therapy. Nucleic acids</searchLink> [Mol Ther Nucleic Acids] 2024 Sep 12; Vol. 35 (4), pp. 102332. <i>Date of Electronic Publication: </i>2024 Sep 12 (<i>Print Publication: </i>2024).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101581621 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>2162-2531 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221622531%22">21622531 </searchLink><i>NLM ISO Abbreviation: </i>Mol Ther Nucleic Acids <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.1016/j.omtn.2024.102332
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              Text: 2024 Sep 12
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