Genomic structural equation modeling reveals latent phenotypes in the human cortex with distinct genetic architecture.
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| Title: | Genomic structural equation modeling reveals latent phenotypes in the human cortex with distinct genetic architecture. |
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| Authors: | Morey RA; Brain Imaging and Analysis Center, Duke University, Durham, NC, 27710, USA.; Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA.; VISN 6 MIRECC, VA Health Care System, Croasdaile Drive, Durham, NC, 27705, USA., Zheng Y; National Center for PTSD, VA Boston Healthcare System, Boston, MA, 02130, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, 02118, USA., Bayly H; National Center for PTSD, VA Boston Healthcare System, Boston, MA, 02130, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, 02118, USA., Sun D; Brain Imaging and Analysis Center, Duke University, Durham, NC, 27710, USA.; Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA.; VISN 6 MIRECC, VA Health Care System, Croasdaile Drive, Durham, NC, 27705, USA., Garrett ME; VISN 6 MIRECC, VA Health Care System, Croasdaile Drive, Durham, NC, 27705, USA.; Department of Medicine, Duke Molecular Physiology Institute, Carmichael Building, Duke University Medical Center, Durham, NC, 27701, USA., Gasperi M; VA Center of Excellence for Stress and Mental Health, VA San Diego Healthcare System, San Diego, CA, 92161, USA.; Research Service VA, San Diego Healthcare System, San Diego, CA, 92161, USA.; Department of Psychiatry, University of California San Diego, La Jolla, CA, 92093, USA., Maihofer AX; Research Service VA, San Diego Healthcare System, San Diego, CA, 92161, USA.; Department of Psychiatry, University of California San Diego, La Jolla, CA, 92093, USA., Baird CL; Brain Imaging and Analysis Center, Duke University, Durham, NC, 27710, USA., Grasby KL; Psychiatric Genetics, QIMR, Berghofer Medical Research Institute, 4006, Brisbane, QLD, Australia., Huggins AA; Brain Imaging and Analysis Center, Duke University, Durham, NC, 27710, USA.; Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA.; VISN 6 MIRECC, VA Health Care System, Croasdaile Drive, Durham, NC, 27705, USA., Haswell CC; Brain Imaging and Analysis Center, Duke University, Durham, NC, 27710, USA.; Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA., Thompson PM; Imaging Genetics Center, Stevens Neuroimaging & Informatics Institute Keck School of Medicine University of Southern California, Los Angeles, CA, 90033, USA., Medland S; Queensland Institute for Medical Research, Berghofer Medical Research Institute, 4006, Brisbane, QLD, Australia., Gustavson DE; Institute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, 80303, USA., Panizzon MS; Stein Institute for Research on Aging, University of California San Diego, La Jolla, CA, 92093, USA., Kremen WS; Stein Institute for Research on Aging, University of California San Diego, La Jolla, CA, 92093, USA., Nievergelt CM; VA Center of Excellence for Stress and Mental Health, VA San Diego Healthcare System, San Diego, CA, 92161, USA.; Research Service VA, San Diego Healthcare System, San Diego, CA, 92161, USA.; Department of Psychiatry, University of California San Diego, La Jolla, CA, 92093, USA., Ashley-Koch AE; VISN 6 MIRECC, VA Health Care System, Croasdaile Drive, Durham, NC, 27705, USA.; Department of Medicine, Duke Molecular Physiology Institute, Carmichael Building, Duke University Medical Center, Durham, NC, 27701, USA., Logue MW; National Center for PTSD, VA Boston Healthcare System, Boston, MA, 02130, USA. loguem@bu.edu.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, 02118, USA. loguem@bu.edu.; Department of Psychiatry, Boston University School of Medicine, Boston, MA, 02118, USA. loguem@bu.edu.; Biomedical Genetics, Boston University School of Medicine, Boston, MA, 02118-2526, USA. loguem@bu.edu. |
| Source: | Translational psychiatry [Transl Psychiatry] 2024 Oct 24; Vol. 14 (1), pp. 451. Date of Electronic Publication: 2024 Oct 24. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101562664 Publication Model: Electronic Cited Medium: Internet ISSN: 2158-3188 (Electronic) Linking ISSN: 21583188 NLM ISO Abbreviation: Transl Psychiatry Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2158-3188 |
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| DOI: | 10.1038/s41398-024-03152-y |
