Spatial, transcriptomic, and epigenomic analyses link dorsal horn neurons to chronic pain genetic predisposition.
Saved in:
| Title: | Spatial, transcriptomic, and epigenomic analyses link dorsal horn neurons to chronic pain genetic predisposition. |
|---|---|
| Authors: | Arokiaraj CM; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA; Pittsburgh Center for Pain Research, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA., Leone MJ; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA; Medical Scientist Training Program, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA., Kleyman M; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA., Chamessian A; Department of Anesthesiology, Duke University Medical Center, Durham, NC 27708, USA; Department of Anesthesiology, Washington University Pain Center, Washington University School of Medicine, St. Louis, MO 63110, USA., Noh MC; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA; Pittsburgh Center for Pain Research, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA., Phan BN; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA; Medical Scientist Training Program, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA., Lopes BC; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA; Pittsburgh Center for Pain Research, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA., Corrigan KA; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA; Pittsburgh Center for Pain Research, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA., Cherupally VK; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA., Yeramosu D; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA., Franusich ME; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA., Podder R; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA., Lele S; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA., Shiers S; Department of Neuroscience and Center for Advanced Pain Studies, University of Texas at Dallas, Richardson, TX 75080, USA., Kang B; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA., Kennedy MM; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA., Chen V; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA., Chen Z; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA; Department of Biological Sciences, Mellon College of Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA., Mathys H; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA., Dum RP; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA., Lewis DA; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA., Qadri Y; Department of Anesthesiology, Emory University, Atlanta, GA 30038, USA., Price TJ; Department of Neuroscience and Center for Advanced Pain Studies, University of Texas at Dallas, Richardson, TX 75080, USA., Pfenning AR; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA; Neuroscience Institute, Carnegie Mellon University, Pittsburgh, PA 15213, USA. Electronic address: apfenning@cmu.edu., Seal RP; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA; Pittsburgh Center for Pain Research, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA; Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA. Electronic address: rpseal@pitt.edu. |
| Source: | Cell reports [Cell Rep] 2024 Nov 26; Vol. 43 (11), pp. 114876. Date of Electronic Publication: 2024 Oct 24. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
|---|---|
| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 39453813 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: Spatial, transcriptomic, and epigenomic analyses link dorsal horn neurons to chronic pain genetic predisposition. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Arokiaraj+CM%22">Arokiaraj CM</searchLink>; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA; Pittsburgh Center for Pain Research, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Leone+MJ%22">Leone MJ</searchLink>; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA; Medical Scientist Training Program, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Kleyman+M%22">Kleyman M</searchLink>; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Chamessian+A%22">Chamessian A</searchLink>; Department of Anesthesiology, Duke University Medical Center, Durham, NC 27708, USA; Department of Anesthesiology, Washington University Pain Center, Washington University School of Medicine, St. Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Noh+MC%22">Noh MC</searchLink>; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA; Pittsburgh Center for Pain Research, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Phan+BN%22">Phan BN</searchLink>; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA; Medical Scientist Training Program, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Lopes+BC%22">Lopes BC</searchLink>; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA; Pittsburgh Center for Pain Research, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Corrigan+KA%22">Corrigan KA</searchLink>; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA; Pittsburgh Center for Pain Research, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Cherupally+VK%22">Cherupally VK</searchLink>; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Yeramosu+D%22">Yeramosu D</searchLink>; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Franusich+ME%22">Franusich ME</searchLink>; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Podder+R%22">Podder R</searchLink>; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Lele+S%22">Lele S</searchLink>; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Shiers+S%22">Shiers S</searchLink>; Department of Neuroscience and Center for Advanced Pain Studies, University of Texas at Dallas, Richardson, TX 75080, USA.<br /><searchLink fieldCode="AU" term="%22Kang+B%22">Kang B</searchLink>; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Kennedy+MM%22">Kennedy MM</searchLink>; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Chen+V%22">Chen V</searchLink>; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Chen+Z%22">Chen Z</searchLink>; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA; Department of Biological Sciences, Mellon College of Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Mathys+H%22">Mathys H</searchLink>; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Dum+RP%22">Dum RP</searchLink>; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Lewis+DA%22">Lewis DA</searchLink>; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.<br /><searchLink fieldCode="AU" term="%22Qadri+Y%22">Qadri Y</searchLink>; Department of Anesthesiology, Emory University, Atlanta, GA 30038, USA.<br /><searchLink fieldCode="AU" term="%22Price+TJ%22">Price TJ</searchLink>; Department of Neuroscience and Center for Advanced Pain Studies, University of Texas at Dallas, Richardson, TX 75080, USA.<br /><searchLink fieldCode="AU" term="%22Pfenning+AR%22">Pfenning AR</searchLink>; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA; Neuroscience Institute, Carnegie Mellon University, Pittsburgh, PA 15213, USA. Electronic address: apfenning@cmu.edu.<br /><searchLink fieldCode="AU" term="%22Seal+RP%22">Seal RP</searchLink>; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA; Pittsburgh Center for Pain Research, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA; Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA. Electronic address: rpseal@pitt.edu. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101573691%22">Cell reports</searchLink> [Cell Rep] 2024 Nov 26; Vol. 43 (11), pp. 114876. <i>Date of Electronic Publication: </i>2024 Oct 24. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, N.I.H., Extramural – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101573691 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2211-1247 (Electronic) <i>NLM ISO Abbreviation: </i>Cell Rep <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=39453813 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.celrep.2024.114876 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 114876 Titles: – TitleFull: Spatial, transcriptomic, and epigenomic analyses link dorsal horn neurons to chronic pain genetic predisposition. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Arokiaraj CM – PersonEntity: Name: NameFull: Leone MJ – PersonEntity: Name: NameFull: Kleyman M – PersonEntity: Name: NameFull: Chamessian A – PersonEntity: Name: NameFull: Noh MC – PersonEntity: Name: NameFull: Phan BN – PersonEntity: Name: NameFull: Lopes BC – PersonEntity: Name: NameFull: Corrigan KA – PersonEntity: Name: NameFull: Cherupally VK – PersonEntity: Name: NameFull: Yeramosu D – PersonEntity: Name: NameFull: Franusich ME – PersonEntity: Name: NameFull: Podder R – PersonEntity: Name: NameFull: Lele S – PersonEntity: Name: NameFull: Shiers S – PersonEntity: Name: NameFull: Kang B – PersonEntity: Name: NameFull: Kennedy MM – PersonEntity: Name: NameFull: Chen V – PersonEntity: Name: NameFull: Chen Z – PersonEntity: Name: NameFull: Mathys H – PersonEntity: Name: NameFull: Dum RP – PersonEntity: Name: NameFull: Lewis DA – PersonEntity: Name: NameFull: Qadri Y – PersonEntity: Name: NameFull: Price TJ – PersonEntity: Name: NameFull: Pfenning AR – PersonEntity: Name: NameFull: Seal RP IsPartOfRelationships: – BibEntity: Dates: – D: 26 M: 11 Text: 2024 Nov 26 Type: published Y: 2024 Identifiers: – Type: issn-electronic Value: 2211-1247 Numbering: – Type: volume Value: 43 – Type: issue Value: 11 Titles: – TitleFull: Cell reports Type: main |
| ResultId | 1 |