Spatial, transcriptomic, and epigenomic analyses link dorsal horn neurons to chronic pain genetic predisposition.

Saved in:
Bibliographic Details
Title: Spatial, transcriptomic, and epigenomic analyses link dorsal horn neurons to chronic pain genetic predisposition.
Authors: Arokiaraj CM; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA; Pittsburgh Center for Pain Research, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA., Leone MJ; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA; Medical Scientist Training Program, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA., Kleyman M; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA., Chamessian A; Department of Anesthesiology, Duke University Medical Center, Durham, NC 27708, USA; Department of Anesthesiology, Washington University Pain Center, Washington University School of Medicine, St. Louis, MO 63110, USA., Noh MC; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA; Pittsburgh Center for Pain Research, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA., Phan BN; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA; Medical Scientist Training Program, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA., Lopes BC; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA; Pittsburgh Center for Pain Research, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA., Corrigan KA; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA; Pittsburgh Center for Pain Research, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA., Cherupally VK; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA., Yeramosu D; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA., Franusich ME; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA., Podder R; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA., Lele S; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA., Shiers S; Department of Neuroscience and Center for Advanced Pain Studies, University of Texas at Dallas, Richardson, TX 75080, USA., Kang B; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA., Kennedy MM; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA., Chen V; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA., Chen Z; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA; Department of Biological Sciences, Mellon College of Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA., Mathys H; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA., Dum RP; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA., Lewis DA; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA., Qadri Y; Department of Anesthesiology, Emory University, Atlanta, GA 30038, USA., Price TJ; Department of Neuroscience and Center for Advanced Pain Studies, University of Texas at Dallas, Richardson, TX 75080, USA., Pfenning AR; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA; Neuroscience Institute, Carnegie Mellon University, Pittsburgh, PA 15213, USA. Electronic address: apfenning@cmu.edu., Seal RP; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA; Pittsburgh Center for Pain Research, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA; Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA. Electronic address: rpseal@pitt.edu.
Source: Cell reports [Cell Rep] 2024 Nov 26; Vol. 43 (11), pp. 114876. Date of Electronic Publication: 2024 Oct 24.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 39453813
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Spatial, transcriptomic, and epigenomic analyses link dorsal horn neurons to chronic pain genetic predisposition.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Arokiaraj+CM%22">Arokiaraj CM</searchLink>; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA; Pittsburgh Center for Pain Research, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Leone+MJ%22">Leone MJ</searchLink>; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA; Medical Scientist Training Program, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Kleyman+M%22">Kleyman M</searchLink>; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Chamessian+A%22">Chamessian A</searchLink>; Department of Anesthesiology, Duke University Medical Center, Durham, NC 27708, USA; Department of Anesthesiology, Washington University Pain Center, Washington University School of Medicine, St. Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Noh+MC%22">Noh MC</searchLink>; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA; Pittsburgh Center for Pain Research, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Phan+BN%22">Phan BN</searchLink>; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA; Medical Scientist Training Program, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Lopes+BC%22">Lopes BC</searchLink>; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA; Pittsburgh Center for Pain Research, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Corrigan+KA%22">Corrigan KA</searchLink>; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA; Pittsburgh Center for Pain Research, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Cherupally+VK%22">Cherupally VK</searchLink>; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Yeramosu+D%22">Yeramosu D</searchLink>; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Franusich+ME%22">Franusich ME</searchLink>; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Podder+R%22">Podder R</searchLink>; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Lele+S%22">Lele S</searchLink>; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Shiers+S%22">Shiers S</searchLink>; Department of Neuroscience and Center for Advanced Pain Studies, University of Texas at Dallas, Richardson, TX 75080, USA.<br /><searchLink fieldCode="AU" term="%22Kang+B%22">Kang B</searchLink>; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Kennedy+MM%22">Kennedy MM</searchLink>; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Chen+V%22">Chen V</searchLink>; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Chen+Z%22">Chen Z</searchLink>; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA; Department of Biological Sciences, Mellon College of Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Mathys+H%22">Mathys H</searchLink>; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Dum+RP%22">Dum RP</searchLink>; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Lewis+DA%22">Lewis DA</searchLink>; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.<br /><searchLink fieldCode="AU" term="%22Qadri+Y%22">Qadri Y</searchLink>; Department of Anesthesiology, Emory University, Atlanta, GA 30038, USA.<br /><searchLink fieldCode="AU" term="%22Price+TJ%22">Price TJ</searchLink>; Department of Neuroscience and Center for Advanced Pain Studies, University of Texas at Dallas, Richardson, TX 75080, USA.<br /><searchLink fieldCode="AU" term="%22Pfenning+AR%22">Pfenning AR</searchLink>; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA; Neuroscience Institute, Carnegie Mellon University, Pittsburgh, PA 15213, USA. Electronic address: apfenning@cmu.edu.<br /><searchLink fieldCode="AU" term="%22Seal+RP%22">Seal RP</searchLink>; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA; Pittsburgh Center for Pain Research, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA; Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA. Electronic address: rpseal@pitt.edu.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101573691%22">Cell reports</searchLink> [Cell Rep] 2024 Nov 26; Vol. 43 (11), pp. 114876. <i>Date of Electronic Publication: </i>2024 Oct 24.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Research Support, N.I.H., Extramural
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101573691 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2211-1247 (Electronic) <i>NLM ISO Abbreviation: </i>Cell Rep <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=39453813
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1016/j.celrep.2024.114876
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 114876
    Titles:
      – TitleFull: Spatial, transcriptomic, and epigenomic analyses link dorsal horn neurons to chronic pain genetic predisposition.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Arokiaraj CM
      – PersonEntity:
          Name:
            NameFull: Leone MJ
      – PersonEntity:
          Name:
            NameFull: Kleyman M
      – PersonEntity:
          Name:
            NameFull: Chamessian A
      – PersonEntity:
          Name:
            NameFull: Noh MC
      – PersonEntity:
          Name:
            NameFull: Phan BN
      – PersonEntity:
          Name:
            NameFull: Lopes BC
      – PersonEntity:
          Name:
            NameFull: Corrigan KA
      – PersonEntity:
          Name:
            NameFull: Cherupally VK
      – PersonEntity:
          Name:
            NameFull: Yeramosu D
      – PersonEntity:
          Name:
            NameFull: Franusich ME
      – PersonEntity:
          Name:
            NameFull: Podder R
      – PersonEntity:
          Name:
            NameFull: Lele S
      – PersonEntity:
          Name:
            NameFull: Shiers S
      – PersonEntity:
          Name:
            NameFull: Kang B
      – PersonEntity:
          Name:
            NameFull: Kennedy MM
      – PersonEntity:
          Name:
            NameFull: Chen V
      – PersonEntity:
          Name:
            NameFull: Chen Z
      – PersonEntity:
          Name:
            NameFull: Mathys H
      – PersonEntity:
          Name:
            NameFull: Dum RP
      – PersonEntity:
          Name:
            NameFull: Lewis DA
      – PersonEntity:
          Name:
            NameFull: Qadri Y
      – PersonEntity:
          Name:
            NameFull: Price TJ
      – PersonEntity:
          Name:
            NameFull: Pfenning AR
      – PersonEntity:
          Name:
            NameFull: Seal RP
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 26
              M: 11
              Text: 2024 Nov 26
              Type: published
              Y: 2024
          Identifiers:
            – Type: issn-electronic
              Value: 2211-1247
          Numbering:
            – Type: volume
              Value: 43
            – Type: issue
              Value: 11
          Titles:
            – TitleFull: Cell reports
              Type: main
ResultId 1