Single-cell landscape of innate and acquired drug resistance in acute myeloid leukemia.
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| Title: | Single-cell landscape of innate and acquired drug resistance in acute myeloid leukemia. |
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| Authors: | Wegmann R; Institute of Molecular Systems Biology, Department of Biology, ETH Zurich, Zurich, Switzerland., Bonilla X; Department of Computer Science, ETH Zurich, Zurich, Switzerland., Casanova R; Department of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland., Chevrier S; Department of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland., Coelho R; Department of Biomedicine, University Hospital Basel and University of Basel, Basel, Switzerland., Esposito C; Institute of Molecular Life Sciences, University of Zurich, Zurich, Switzerland., Ficek-Pascual J; Department of Computer Science, ETH Zurich, Zurich, Switzerland., Goetze S; Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland.; ETH PHRT Swiss Multi-Omics Center (SMOC), Lausanne, Switzerland.; SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland., Gut G; Institute of Molecular Life Sciences, University of Zurich, Zurich, Switzerland., Jacob F; Department of Biomedicine, University Hospital Basel and University of Basel, Basel, Switzerland., Jacobs A; Department of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland., Kuipers J; Department of Biosystems Science and Engineering, ETH Zurich, Zurich, Switzerland., Lischetti U; Department of Biomedicine, University Hospital Basel and University of Basel, Basel, Switzerland., Mena J; Institute of Molecular Systems Biology, Department of Biology, ETH Zurich, Zurich, Switzerland., Milani ES; Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland., Prummer M; SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland.; NEXUS Personalized Health Technologies, ETH Zurich, Zurich, Switzerland., Del Castillo JS; Institute of Molecular Life Sciences, University of Zurich, Zurich, Switzerland., Singer F; SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland.; NEXUS Personalized Health Technologies, ETH Zurich, Zurich, Switzerland., Sivapatham S; Department of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland., Toussaint NC; SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland.; NEXUS Personalized Health Technologies, ETH Zurich, Zurich, Switzerland.; Swiss Data Science Center, ETH Zürich, Zurich, Switzerland., Vilinovszki O; Department of Medical Oncology and Hematology, University Hospital Zurich, Zurich, Switzerland., Wildschut MHE; Institute of Molecular Systems Biology, Department of Biology, ETH Zurich, Zurich, Switzerland.; Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland.; Department of Medical Oncology and Hematology, University Hospital Zurich, Zurich, Switzerland., Thavayogarajah T; Department of Medical Oncology and Hematology, University Hospital Zurich, Zurich, Switzerland., Malani D; Harvard Medical School and Dana-Farber Cancer Institute, Boston, USA., Aebersold R; Institute of Molecular Systems Biology, Department of Biology, ETH Zurich, Zurich, Switzerland., Bacac M; Roche Pharmaceutical Research and Early Development, Roche Innovation Center Zurich, Zurich, Switzerland., Beerenwinkel N; SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland.; Department of Biosystems Science and Engineering, ETH Zurich, Zurich, Switzerland., Beisel C; Department of Biosystems Science and Engineering, ETH Zurich, Zurich, Switzerland., Bodenmiller B; Department of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland.; Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland., Heinzelmann-Schwarz V; Department of Biomedicine, University Hospital Basel and University of Basel, Basel, Switzerland., Koelzer VH; Department of Pathology and Molecular Pathology, University Hospital Zurich, Zurich, Switzerland.; University of Zurich, Faculty of Medicine, Zurich, Switzerland., Levesque MP; Department of Dermatology, University Hospital Zurich, Zurich, Switzerland., Moch H; Department of Pathology and Molecular Pathology, University Hospital Zurich, Zurich, Switzerland.; University of Zurich, Faculty of Medicine, Zurich, Switzerland., Pelkmans L; Institute of Molecular Life Sciences, University of Zurich, Zurich, Switzerland., Rätsch G; Department of Computer Science, ETH Zurich, Zurich, Switzerland.; SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland.; AI Center at ETH Zurich, Zurich, Switzerland., Tolnay M; Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland., Wicki A; Department of Medical Oncology and Hematology, University Hospital Zurich, Zurich, Switzerland.; University of Zurich, Faculty of Medicine, Zurich, Switzerland., Wollscheid B; Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland., Manz MG; Department of Medical Oncology and Hematology, University Hospital Zurich, Zurich, Switzerland. markus.manz@usz.ch., Snijder B; Institute of Molecular Systems Biology, Department of Biology, ETH Zurich, Zurich, Switzerland. snijder@imsb.biol.ethz.ch.; SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland. snijder@imsb.biol.ethz.ch., Theocharides APA; Department of Medical Oncology and Hematology, University Hospital Zurich, Zurich, Switzerland. alexandre.theocharides@usz.ch. |
| Corporate Authors: | TumorProfiler Consortium |
| Source: | Nature communications [Nat Commun] 2024 Oct 30; Vol. 15 (1), pp. 9402. Date of Electronic Publication: 2024 Oct 30. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 39477946 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Single-cell landscape of innate and acquired drug resistance in acute myeloid leukemia. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Wegmann+R%22">Wegmann R</searchLink>; Institute of Molecular Systems Biology, Department of Biology, ETH Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Bonilla+X%22">Bonilla X</searchLink>; Department of Computer Science, ETH Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Casanova+R%22">Casanova R</searchLink>; Department of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Chevrier+S%22">Chevrier S</searchLink>; Department of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Coelho+R%22">Coelho R</searchLink>; Department of Biomedicine, University Hospital Basel and University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Esposito+C%22">Esposito C</searchLink>; Institute of Molecular Life Sciences, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Ficek-Pascual+J%22">Ficek-Pascual J</searchLink>; Department of Computer Science, ETH Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Goetze+S%22">Goetze S</searchLink>; Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland.; ETH PHRT Swiss Multi-Omics Center (SMOC), Lausanne, Switzerland.; SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Gut+G%22">Gut G</searchLink>; Institute of Molecular Life Sciences, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Jacob+F%22">Jacob F</searchLink>; Department of Biomedicine, University Hospital Basel and University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Jacobs+A%22">Jacobs A</searchLink>; Department of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Kuipers+J%22">Kuipers J</searchLink>; Department of Biosystems Science and Engineering, ETH Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Lischetti+U%22">Lischetti U</searchLink>; Department of Biomedicine, University Hospital Basel and University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Mena+J%22">Mena J</searchLink>; Institute of Molecular Systems Biology, Department of Biology, ETH Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Milani+ES%22">Milani ES</searchLink>; Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Prummer+M%22">Prummer M</searchLink>; SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland.; NEXUS Personalized Health Technologies, ETH Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Del+Castillo+JS%22">Del Castillo JS</searchLink>; Institute of Molecular Life Sciences, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Singer+F%22">Singer F</searchLink>; SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland.; NEXUS Personalized Health Technologies, ETH Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Sivapatham+S%22">Sivapatham S</searchLink>; Department of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Toussaint+NC%22">Toussaint NC</searchLink>; SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland.; NEXUS Personalized Health Technologies, ETH Zurich, Zurich, Switzerland.; Swiss Data Science Center, ETH Zürich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Vilinovszki+O%22">Vilinovszki O</searchLink>; Department of Medical Oncology and Hematology, University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Wildschut+MHE%22">Wildschut MHE</searchLink>; Institute of Molecular Systems Biology, Department of Biology, ETH Zurich, Zurich, Switzerland.; Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland.; Department of Medical Oncology and Hematology, University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Thavayogarajah+T%22">Thavayogarajah T</searchLink>; Department of Medical Oncology and Hematology, University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Malani+D%22">Malani D</searchLink>; Harvard Medical School and Dana-Farber Cancer Institute, Boston, USA.<br /><searchLink fieldCode="AU" term="%22Aebersold+R%22">Aebersold R</searchLink>; Institute of Molecular Systems Biology, Department of Biology, ETH Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Bacac+M%22">Bacac M</searchLink>; Roche Pharmaceutical Research and Early Development, Roche Innovation Center Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Beerenwinkel+N%22">Beerenwinkel N</searchLink>; SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland.; Department of Biosystems Science and Engineering, ETH Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Beisel+C%22">Beisel C</searchLink>; Department of Biosystems Science and Engineering, ETH Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Bodenmiller+B%22">Bodenmiller B</searchLink>; Department of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland.; Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Heinzelmann-Schwarz+V%22">Heinzelmann-Schwarz V</searchLink>; Department of Biomedicine, University Hospital Basel and University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Koelzer+VH%22">Koelzer VH</searchLink>; Department of Pathology and Molecular Pathology, University Hospital Zurich, Zurich, Switzerland.; University of Zurich, Faculty of Medicine, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Levesque+MP%22">Levesque MP</searchLink>; Department of Dermatology, University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Moch+H%22">Moch H</searchLink>; Department of Pathology and Molecular Pathology, University Hospital Zurich, Zurich, Switzerland.; University of Zurich, Faculty of Medicine, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Pelkmans+L%22">Pelkmans L</searchLink>; Institute of Molecular Life Sciences, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Rätsch+G%22">Rätsch G</searchLink>; Department of Computer Science, ETH Zurich, Zurich, Switzerland.; SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland.; AI Center at ETH Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Tolnay+M%22">Tolnay M</searchLink>; Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Wicki+A%22">Wicki A</searchLink>; Department of Medical Oncology and Hematology, University Hospital Zurich, Zurich, Switzerland.; University of Zurich, Faculty of Medicine, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Wollscheid+B%22">Wollscheid B</searchLink>; Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Manz+MG%22">Manz MG</searchLink>; Department of Medical Oncology and Hematology, University Hospital Zurich, Zurich, Switzerland. markus.manz@usz.ch.<br /><searchLink fieldCode="AU" term="%22Snijder+B%22">Snijder B</searchLink>; Institute of Molecular Systems Biology, Department of Biology, ETH Zurich, Zurich, Switzerland. snijder@imsb.biol.ethz.ch.; SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland. snijder@imsb.biol.ethz.ch.<br /><searchLink fieldCode="AU" term="%22Theocharides+APA%22">Theocharides APA</searchLink>; Department of Medical Oncology and Hematology, University Hospital Zurich, Zurich, Switzerland. alexandre.theocharides@usz.ch. – Name: AuthorCorporate Label: Corporate Authors Group: Au Data: <searchLink fieldCode="CA" term="%22TumorProfiler+Consortium%22">TumorProfiler Consortium</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2024 Oct 30; Vol. 15 (1), pp. 9402. <i>Date of Electronic Publication: </i>2024 Oct 30. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. 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