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ZNFX1 is a Novel Master Regulator in Epigenetically-induced Pathogen Mimicry and Inflammasome Signaling in Cancer.

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Title: ZNFX1 is a Novel Master Regulator in Epigenetically-induced Pathogen Mimicry and Inflammasome Signaling in Cancer.
Authors: Stojanovic L; University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center, Baltimore, MD 21201, USA.; Division of Translational Radiation Sciences, Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Abbotts R; University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center, Baltimore, MD 21201, USA.; Division of Translational Radiation Sciences, Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Tripathi K; University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center, Baltimore, MD 21201, USA.; Division of Translational Radiation Sciences, Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Coon CM; Medical Sciences Program, Indiana University School of Medicine-Bloomington, Bloomington, IN 47405, USA., Rajendran S; Medical Sciences Program, Indiana University School of Medicine-Bloomington, Bloomington, IN 47405, USA., Farid EA; Medical Sciences Program, Indiana University School of Medicine-Bloomington, Bloomington, IN 47405, USA., Hostetter G; Van Andel Research Institute, Grand Rapids, MI 49503, USA., Guarnieri JW; Center for Mitochondrial and Epigenomic Medicine, Division of Human Genetics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA., Wallace DC; Center for Mitochondrial and Epigenomic Medicine, Division of Human Genetics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.; Department of Pediatrics, Division of Human Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Liu S; Department of Medical and Molecular Genetics, Indiana University School of Medicine Indianapolis, IN 46202, USA.; Department of Anatomy, Cell Biology and Physiology, Indiana University School of Medicine Indianapolis, IN 46202, USA., Wan J; Department of Medical and Molecular Genetics, Indiana University School of Medicine Indianapolis, IN 46202, USA.; Department of Anatomy, Cell Biology and Physiology, Indiana University School of Medicine Indianapolis, IN 46202, USA., Calendo G; Coriell Institute for Medical Research, Camden, NJ 08103., Marker R; Division of Translational Radiation Sciences, Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Gohari Z; University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center, Baltimore, MD 21201, USA.; Division of Translational Radiation Sciences, Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Inayatullah MMA; University of Southern Denmark, Odense, Denmark., Tiwari VK; University of Southern Denmark, Odense, Denmark., Kader T; Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA, USA.; Ludwig Center at Harvard, Boston, MA, USA., Santagata S; Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA, USA.; Ludwig Center at Harvard, Boston, MA, USA.; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Drapkin R; Penn Ovarian Cancer Research Center, Department of Obstetrics and Gynecology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.; Basser Center for BRCA, Abramson Cancer Center, University of Pennsylvania School of Medicine, Philadelphia, PA, USA., Kommoss S; Diakonie-Klinikum Schwäbisch Hall, Germany, Institute for Health Informatics.; Kliniken Essen-Mitte, Gynäkologie und Gynäkologische Onkologie, Germany., Pfisterer J; Department of Medicine, David Geffen School of Medicine., Konecny GE; University of California Los Angeles, Los Angeles, CA., Coopergard R; Institute for Health Informatics, University of Minnesota, Minneapolis, MN 55455, USA., Issa JP; Coriell Institute for Medical Research, Camden, NJ 08103., Winterhoff BJN; Department of Obstetrics, Gynecology and Women's Health (OBGYN), Division of Gynecologic Oncology, University of Minnesota, MN 55812-3011, USA., Topper MJ; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21231, USA., Sandusky GE; Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA.; Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis, IN 46202, USA., Miller KD; Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis, IN 46202, USA.; Department of Medicine, Division of Hematology/Oncology, Indiana University School of Medicine, Indianapolis, IN 46202, USA., Baylin SB; Diakonie-Klinikum Schwäbisch Hall, Germany, Institute for Health Informatics.; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21231, USA., Nephew KP; Medical Sciences Program, Indiana University School of Medicine-Bloomington, Bloomington, IN 47405, USA.; Department of Anatomy, Cell Biology and Physiology, Indiana University School of Medicine Indianapolis, IN 46202, USA.; Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis, IN 46202, USA., Rassool FV; University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center, Baltimore, MD 21201, USA.; Division of Translational Radiation Sciences, Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2024 Oct 21. Date of Electronic Publication: 2024 Oct 21.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: ZNFX1 is a Novel Master Regulator in Epigenetically-induced Pathogen Mimicry and Inflammasome Signaling in Cancer.
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  Data: <searchLink fieldCode="AU" term="%22Stojanovic+L%22">Stojanovic L</searchLink>; University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center, Baltimore, MD 21201, USA.; Division of Translational Radiation Sciences, Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.<br /><searchLink fieldCode="AU" term="%22Abbotts+R%22">Abbotts R</searchLink>; University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center, Baltimore, MD 21201, USA.; Division of Translational Radiation Sciences, Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.<br /><searchLink fieldCode="AU" term="%22Tripathi+K%22">Tripathi K</searchLink>; University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center, Baltimore, MD 21201, USA.; Division of Translational Radiation Sciences, Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.<br /><searchLink fieldCode="AU" term="%22Coon+CM%22">Coon CM</searchLink>; Medical Sciences Program, Indiana University School of Medicine-Bloomington, Bloomington, IN 47405, USA.<br /><searchLink fieldCode="AU" term="%22Rajendran+S%22">Rajendran S</searchLink>; Medical Sciences Program, Indiana University School of Medicine-Bloomington, Bloomington, IN 47405, USA.<br /><searchLink fieldCode="AU" term="%22Farid+EA%22">Farid EA</searchLink>; Medical Sciences Program, Indiana University School of Medicine-Bloomington, Bloomington, IN 47405, USA.<br /><searchLink fieldCode="AU" term="%22Hostetter+G%22">Hostetter G</searchLink>; Van Andel Research Institute, Grand Rapids, MI 49503, USA.<br /><searchLink fieldCode="AU" term="%22Guarnieri+JW%22">Guarnieri JW</searchLink>; Center for Mitochondrial and Epigenomic Medicine, Division of Human Genetics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Wallace+DC%22">Wallace DC</searchLink>; Center for Mitochondrial and Epigenomic Medicine, Division of Human Genetics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.; Department of Pediatrics, Division of Human Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Liu+S%22">Liu S</searchLink>; Department of Medical and Molecular Genetics, Indiana University School of Medicine Indianapolis, IN 46202, USA.; Department of Anatomy, Cell Biology and Physiology, Indiana University School of Medicine Indianapolis, IN 46202, USA.<br /><searchLink fieldCode="AU" term="%22Wan+J%22">Wan J</searchLink>; Department of Medical and Molecular Genetics, Indiana University School of Medicine Indianapolis, IN 46202, USA.; Department of Anatomy, Cell Biology and Physiology, Indiana University School of Medicine Indianapolis, IN 46202, USA.<br /><searchLink fieldCode="AU" term="%22Calendo+G%22">Calendo G</searchLink>; Coriell Institute for Medical Research, Camden, NJ 08103.<br /><searchLink fieldCode="AU" term="%22Marker+R%22">Marker R</searchLink>; Division of Translational Radiation Sciences, Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.<br /><searchLink fieldCode="AU" term="%22Gohari+Z%22">Gohari Z</searchLink>; University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center, Baltimore, MD 21201, USA.; Division of Translational Radiation Sciences, Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.<br /><searchLink fieldCode="AU" term="%22Inayatullah+MMA%22">Inayatullah MMA</searchLink>; University of Southern Denmark, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Tiwari+VK%22">Tiwari VK</searchLink>; University of Southern Denmark, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Kader+T%22">Kader T</searchLink>; Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA, USA.; Ludwig Center at Harvard, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Santagata+S%22">Santagata S</searchLink>; Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA, USA.; Ludwig Center at Harvard, Boston, MA, USA.; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Drapkin+R%22">Drapkin R</searchLink>; Penn Ovarian Cancer Research Center, Department of Obstetrics and Gynecology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.; Basser Center for BRCA, Abramson Cancer Center, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Kommoss+S%22">Kommoss S</searchLink>; Diakonie-Klinikum Schwäbisch Hall, Germany, Institute for Health Informatics.; Kliniken Essen-Mitte, Gynäkologie und Gynäkologische Onkologie, Germany.<br /><searchLink fieldCode="AU" term="%22Pfisterer+J%22">Pfisterer J</searchLink>; Department of Medicine, David Geffen School of Medicine.<br /><searchLink fieldCode="AU" term="%22Konecny+GE%22">Konecny GE</searchLink>; University of California Los Angeles, Los Angeles, CA.<br /><searchLink fieldCode="AU" term="%22Coopergard+R%22">Coopergard R</searchLink>; Institute for Health Informatics, University of Minnesota, Minneapolis, MN 55455, USA.<br /><searchLink fieldCode="AU" term="%22Issa+JP%22">Issa JP</searchLink>; Coriell Institute for Medical Research, Camden, NJ 08103.<br /><searchLink fieldCode="AU" term="%22Winterhoff+BJN%22">Winterhoff BJN</searchLink>; Department of Obstetrics, Gynecology and Women's Health (OBGYN), Division of Gynecologic Oncology, University of Minnesota, MN 55812-3011, USA.<br /><searchLink fieldCode="AU" term="%22Topper+MJ%22">Topper MJ</searchLink>; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21231, USA.<br /><searchLink fieldCode="AU" term="%22Sandusky+GE%22">Sandusky GE</searchLink>; Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA.; Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis, IN 46202, USA.<br /><searchLink fieldCode="AU" term="%22Miller+KD%22">Miller KD</searchLink>; Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis, IN 46202, USA.; Department of Medicine, Division of Hematology/Oncology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.<br /><searchLink fieldCode="AU" term="%22Baylin+SB%22">Baylin SB</searchLink>; Diakonie-Klinikum Schwäbisch Hall, Germany, Institute for Health Informatics.; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21231, USA.<br /><searchLink fieldCode="AU" term="%22Nephew+KP%22">Nephew KP</searchLink>; Medical Sciences Program, Indiana University School of Medicine-Bloomington, Bloomington, IN 47405, USA.; Department of Anatomy, Cell Biology and Physiology, Indiana University School of Medicine Indianapolis, IN 46202, USA.; Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis, IN 46202, USA.<br /><searchLink fieldCode="AU" term="%22Rassool+FV%22">Rassool FV</searchLink>; University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center, Baltimore, MD 21201, USA.; Division of Translational Radiation Sciences, Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
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