Adavosertib in Combination with Olaparib in Patients with Refractory Solid Tumors: An Open-Label, Dose-Finding, and Dose-Expansion Phase Ib Trial.
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| Title: | Adavosertib in Combination with Olaparib in Patients with Refractory Solid Tumors: An Open-Label, Dose-Finding, and Dose-Expansion Phase Ib Trial. |
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| Authors: | Hamilton EP; Sarah Cannon Research Institute, 250 25th Avenue North, Nashville, TN, 37203, USA. Erika.Hamilton@scri.com., Falchook GS; Sarah Cannon Research Institute at HealthONE, Denver, CO, USA., Wang JS; Sarah Cannon Research Institute, 250 25th Avenue North, Nashville, TN, 37203, USA.; Florida Cancer Specialists, Sarasota, FL, USA., Fu S; MD Anderson Cancer Center, Houston, TX, USA., Oza AM; Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Canada., Imedio ER; Oncology R&D, AstraZeneca, Cambridge, UK., Kumar S; Oncology R&D, AstraZeneca, Cambridge, UK., Ottesen L; Oncology R&D, AstraZeneca, Cambridge, UK., Mugundu GM; Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Boston, MA, USA., de Bruin EC; Oncology R&D, AstraZeneca, Cambridge, UK., O'Connor MJ; Oncology R&D, AstraZeneca, Cambridge, UK., Jones SF; Sarah Cannon Research Institute, 250 25th Avenue North, Nashville, TN, 37203, USA., Spigel DR; Sarah Cannon Research Institute, 250 25th Avenue North, Nashville, TN, 37203, USA., Li BT; Memorial Sloan Kettering Cancer Center, New York, NY, USA. |
| Source: | Targeted oncology [Target Oncol] 2024 Nov; Vol. 19 (6), pp. 879-892. Date of Electronic Publication: 2024 Nov 01. |
| Publication Type: | Journal Article; Clinical Trial, Phase I; Multicenter Study; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Springer-Verlag France Country of Publication: France NLM ID: 101270595 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1776-260X (Electronic) Linking ISSN: 17762596 NLM ISO Abbreviation: Target Oncol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1776-260X |
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| DOI: | 10.1007/s11523-024-01102-8 |
