Bio-orthogonal tuning of matrix properties during 3D cell culture to induce morphological and phenotypic changes.

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Title: Bio-orthogonal tuning of matrix properties during 3D cell culture to induce morphological and phenotypic changes.
Authors: Gao H; Department of Materials Science and Engineering, University of Delaware, Newark, DE, USA., Pol M; Department of Biological Sciences, University of Delaware, Newark, DE, USA., Makara CA; Department of Chemistry and Biochemistry, University of Delaware, Newark, DE, USA., Song J; Department of Materials Science and Engineering, University of Delaware, Newark, DE, USA., Zhang H; Department of Materials Science and Engineering, University of Delaware, Newark, DE, USA., Zou X; Department of Materials Science and Engineering, University of Delaware, Newark, DE, USA., Benson JM; Department of Biomedical Engineering, University of Delaware, Newark, DE, USA., Burris DL; Department of Mechanical Engineering, University of Delaware, Newark, DE, USA., Fox JM; Department of Materials Science and Engineering, University of Delaware, Newark, DE, USA.; Department of Chemistry and Biochemistry, University of Delaware, Newark, DE, USA., Jia X; Department of Materials Science and Engineering, University of Delaware, Newark, DE, USA. xjia@udel.edu.; Department of Biological Sciences, University of Delaware, Newark, DE, USA. xjia@udel.edu.; Department of Biomedical Engineering, University of Delaware, Newark, DE, USA. xjia@udel.edu.; Delaware Biotechnology Institute, University of Delaware, Newark, DE, USA. xjia@udel.edu.
Source: Nature protocols [Nat Protoc] 2025 Mar; Vol. 20 (3), pp. 727-778. Date of Electronic Publication: 2024 Nov 05.
Publication Type: Journal Article; Review; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101284307 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1750-2799 (Electronic) Linking ISSN: 17502799 NLM ISO Abbreviation: Nat Protoc Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1750-2799
DOI:10.1038/s41596-024-01066-z