Lipotoxicity of palmitic acid is associated with DGAT1 downregulation and abolished by PPARα activation in liver cells.

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Title: Lipotoxicity of palmitic acid is associated with DGAT1 downregulation and abolished by PPARα activation in liver cells.
Authors: Moliterni C; Department of Biology and Biotechnology 'C. Darwin', Sapienza University of Rome, Rome, Italy., Vari F; Department of Biological and Environmental Sciences and Technologies, University of Salento, Lecce, Italy; Department of Physiology and Pharmacology 'V. Erspamer', Sapienza University of Rome, Rome, Italy., Schifano E; Department of Biology and Biotechnology 'C. Darwin', Sapienza University of Rome, Rome, Italy., Tacconi S; Department of Biology and Biotechnology 'C. Darwin', Sapienza University of Rome, Rome, Italy., Stanca E; Department of Biological and Environmental Sciences and Technologies, University of Salento, Lecce, Italy., Friuli M; Department of Physiology and Pharmacology 'V. Erspamer', Sapienza University of Rome, Rome, Italy., Longo S; Department of Biological and Environmental Sciences and Technologies, University of Salento, Lecce, Italy., Conte M; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy., Salvioli S; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Gnocchi D; Interdisciplinary Department of Medicine, University of Bari School of Medicine, Bari, Italy., Mazzocca A; Interdisciplinary Department of Medicine, University of Bari School of Medicine, Bari, Italy., Uccelletti D; Department of Biology and Biotechnology 'C. Darwin', Sapienza University of Rome, Rome, Italy., Vergara D; Department of Biological and Environmental Sciences and Technologies, University of Salento, Lecce, Italy., Dini L; Department of Biology and Biotechnology 'C. Darwin', Sapienza University of Rome, Rome, Italy. Electronic address: luciana.dini@uniroma1.it., Giudetti AM; Department of Biological and Environmental Sciences and Technologies, University of Salento, Lecce, Italy. Electronic address: anna.giudetti@unisalento.it.
Source: Journal of lipid research [J Lipid Res] 2024 Dec; Vol. 65 (12), pp. 100692. Date of Electronic Publication: 2024 Nov 05.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0376606 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1539-7262 (Electronic) Linking ISSN: 00222275 NLM ISO Abbreviation: J Lipid Res Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1539-7262
DOI:10.1016/j.jlr.2024.100692