Lysosomal enzyme binding to the cation-independent mannose 6-phosphate receptor is regulated allosterically by insulin-like growth factor 2.

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Title: Lysosomal enzyme binding to the cation-independent mannose 6-phosphate receptor is regulated allosterically by insulin-like growth factor 2.
Authors: Bohnsack RN; Department of Biochemistry, Medical College of Wisconsin, 8701 W. Watertown Plank Rd., Milwaukee, WI, 53226, USA., Misra SK; Department of BioMolecular Sciences, University of Mississippi, Oxford, MS, 38677, USA., Liu J; The Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA., Ishihara-Aoki M; Translational Metabolomics Shared Resource, Cancer Center, Medical College of Wisconsin, Milwaukee, WI, 53226, USA., Pereckas M; Department of Biochemistry, Medical College of Wisconsin, 8701 W. Watertown Plank Rd., Milwaukee, WI, 53226, USA., Aoki K; Translational Metabolomics Shared Resource, Cancer Center, Medical College of Wisconsin, Milwaukee, WI, 53226, USA.; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI, 53226, USA., Ren G; The Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA., Sharp JS; Department of BioMolecular Sciences, University of Mississippi, Oxford, MS, 38677, USA.; Department of Chemistry and Biochemistry, University of Mississippi, Oxford, MS, 38677, USA., Dahms NM; Department of Biochemistry, Medical College of Wisconsin, 8701 W. Watertown Plank Rd., Milwaukee, WI, 53226, USA. ndahms@mcw.edu.
Source: Scientific reports [Sci Rep] 2024 Nov 06; Vol. 14 (1), pp. 26875. Date of Electronic Publication: 2024 Nov 06.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2045-2322
DOI:10.1038/s41598-024-75300-9