Transcriptomic heterogeneity of non-beta islet cells is associated with type 2 diabetes development in mouse models.

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Title: Transcriptomic heterogeneity of non-beta islet cells is associated with type 2 diabetes development in mouse models.
Authors: Gottmann P; Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Nuthetal, Germany.; German Center for Diabetes Research (DZD), München Neuherberg, Germany., Speckmann T; Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Nuthetal, Germany.; German Center for Diabetes Research (DZD), München Neuherberg, Germany., Stadion M; Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Nuthetal, Germany.; German Center for Diabetes Research (DZD), München Neuherberg, Germany., Chawla P; German Center for Diabetes Research (DZD), München Neuherberg, Germany.; Center for Regenerative Therapies TU Dresden, Dresden, Germany., Saurenbach J; Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Nuthetal, Germany.; German Center for Diabetes Research (DZD), München Neuherberg, Germany., Ninov N; German Center for Diabetes Research (DZD), München Neuherberg, Germany.; Center for Regenerative Therapies TU Dresden, Dresden, Germany., Lickert H; German Center for Diabetes Research (DZD), München Neuherberg, Germany.; Institute of Diabetes and Regeneration Research, Helmholtz Center Munich, Neuherberg, Germany.; Institute of Stem Cell Research, Helmholtz Center Munich, Neuherberg, Germany., Schürmann A; Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Nuthetal, Germany. schuermann@dife.de.; German Center for Diabetes Research (DZD), München Neuherberg, Germany. schuermann@dife.de.; University of Potsdam, Institute of Nutritional Sciences, Nuthetal, Germany. schuermann@dife.de.
Source: Diabetologia [Diabetologia] 2025 Jan; Vol. 68 (1), pp. 166-185. Date of Electronic Publication: 2024 Nov 07.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0006777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0428 (Electronic) Linking ISSN: 0012186X NLM ISO Abbreviation: Diabetologia Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1432-0428
DOI:10.1007/s00125-024-06301-6