Development of a Versatile Cancer Vaccine Format Targeting Antigen-Presenting Cells Using Proximity-Based Sortase A-Mediated Ligation of T-Cell Epitopes.

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Title: Development of a Versatile Cancer Vaccine Format Targeting Antigen-Presenting Cells Using Proximity-Based Sortase A-Mediated Ligation of T-Cell Epitopes.
Authors: Wang AZ; Department of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, 1081 HV Amsterdam, The Netherlands., Brink HJ; Department of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, 1081 HV Amsterdam, The Netherlands., Bouma RG; Department of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, 1081 HV Amsterdam, The Netherlands., Affandi AJ; Department of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, 1081 HV Amsterdam, The Netherlands., Nijen Twilhaar MK; Department of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, 1081 HV Amsterdam, The Netherlands., Heijnen DAM; Department of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, 1081 HV Amsterdam, The Netherlands., van Elk J; Department of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, 1081 HV Amsterdam, The Netherlands., Maaskant JJ; Department of Medical Microbiology and Infection Control, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands., Konijn VAL; Department of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, 1081 HV Amsterdam, The Netherlands., Stolwijk JGC; Department of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, 1081 HV Amsterdam, The Netherlands., Kalay H; Department of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, 1081 HV Amsterdam, The Netherlands., Olesek K; Department of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, 1081 HV Amsterdam, The Netherlands., van Kooyk Y; Department of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, 1081 HV Amsterdam, The Netherlands., van der Schoot JMS; Department of Medical Biosciences, Institute for Chemical Immunology, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands., Bentlage AEH; Sanquin Research, 1066 CX Amsterdam, The Netherlands., Scheeren FA; Department of Dermatology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands., Verdoes M; Department of Medical Biosciences, Institute for Chemical Immunology, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands., Vidarsson G; Sanquin Research, 1066 CX Amsterdam, The Netherlands.; Department of Biomolecular Mass Spectrometry and Proteomics, Utrecht Institute for Pharmaceutical Sciences and Bijvoet Center for Biomolecular Research, Utrecht University, 3508 TC Utrecht, The Netherlands., Kuijl CP; Department of Medical Microbiology and Infection Control, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands., den Haan JMM; Department of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, 1081 HV Amsterdam, The Netherlands.
Source: Bioconjugate chemistry [Bioconjug Chem] 2024 Nov 20; Vol. 35 (11), pp. 1805-1814. Date of Electronic Publication: 2024 Nov 07.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9010319 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4812 (Electronic) Linking ISSN: 10431802 NLM ISO Abbreviation: Bioconjug Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1520-4812
DOI:10.1021/acs.bioconjchem.4c00403