Development of a Versatile Cancer Vaccine Format Targeting Antigen-Presenting Cells Using Proximity-Based Sortase A-Mediated Ligation of T-Cell Epitopes.

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Title: Development of a Versatile Cancer Vaccine Format Targeting Antigen-Presenting Cells Using Proximity-Based Sortase A-Mediated Ligation of T-Cell Epitopes.
Authors: Wang AZ; Department of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, 1081 HV Amsterdam, The Netherlands., Brink HJ; Department of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, 1081 HV Amsterdam, The Netherlands., Bouma RG; Department of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, 1081 HV Amsterdam, The Netherlands., Affandi AJ; Department of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, 1081 HV Amsterdam, The Netherlands., Nijen Twilhaar MK; Department of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, 1081 HV Amsterdam, The Netherlands., Heijnen DAM; Department of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, 1081 HV Amsterdam, The Netherlands., van Elk J; Department of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, 1081 HV Amsterdam, The Netherlands., Maaskant JJ; Department of Medical Microbiology and Infection Control, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands., Konijn VAL; Department of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, 1081 HV Amsterdam, The Netherlands., Stolwijk JGC; Department of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, 1081 HV Amsterdam, The Netherlands., Kalay H; Department of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, 1081 HV Amsterdam, The Netherlands., Olesek K; Department of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, 1081 HV Amsterdam, The Netherlands., van Kooyk Y; Department of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, 1081 HV Amsterdam, The Netherlands., van der Schoot JMS; Department of Medical Biosciences, Institute for Chemical Immunology, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands., Bentlage AEH; Sanquin Research, 1066 CX Amsterdam, The Netherlands., Scheeren FA; Department of Dermatology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands., Verdoes M; Department of Medical Biosciences, Institute for Chemical Immunology, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands., Vidarsson G; Sanquin Research, 1066 CX Amsterdam, The Netherlands.; Department of Biomolecular Mass Spectrometry and Proteomics, Utrecht Institute for Pharmaceutical Sciences and Bijvoet Center for Biomolecular Research, Utrecht University, 3508 TC Utrecht, The Netherlands., Kuijl CP; Department of Medical Microbiology and Infection Control, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands., den Haan JMM; Department of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, 1081 HV Amsterdam, The Netherlands.
Source: Bioconjugate chemistry [Bioconjug Chem] 2024 Nov 20; Vol. 35 (11), pp. 1805-1814. Date of Electronic Publication: 2024 Nov 07.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9010319 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4812 (Electronic) Linking ISSN: 10431802 NLM ISO Abbreviation: Bioconjug Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Development of a Versatile Cancer Vaccine Format Targeting Antigen-Presenting Cells Using Proximity-Based Sortase A-Mediated Ligation of T-Cell Epitopes.
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  Data: <searchLink fieldCode="AU" term="%22Wang+AZ%22">Wang AZ</searchLink>; Department of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, 1081 HV Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Brink+HJ%22">Brink HJ</searchLink>; Department of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, 1081 HV Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Bouma+RG%22">Bouma RG</searchLink>; Department of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, 1081 HV Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Affandi+AJ%22">Affandi AJ</searchLink>; Department of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, 1081 HV Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Nijen+Twilhaar+MK%22">Nijen Twilhaar MK</searchLink>; Department of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, 1081 HV Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Heijnen+DAM%22">Heijnen DAM</searchLink>; Department of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, 1081 HV Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Elk+J%22">van Elk J</searchLink>; Department of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, 1081 HV Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Maaskant+JJ%22">Maaskant JJ</searchLink>; Department of Medical Microbiology and Infection Control, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Konijn+VAL%22">Konijn VAL</searchLink>; Department of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, 1081 HV Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Stolwijk+JGC%22">Stolwijk JGC</searchLink>; Department of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, 1081 HV Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Kalay+H%22">Kalay H</searchLink>; Department of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, 1081 HV Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Olesek+K%22">Olesek K</searchLink>; Department of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, 1081 HV Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Kooyk+Y%22">van Kooyk Y</searchLink>; Department of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, 1081 HV Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+der+Schoot+JMS%22">van der Schoot JMS</searchLink>; Department of Medical Biosciences, Institute for Chemical Immunology, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Bentlage+AEH%22">Bentlage AEH</searchLink>; Sanquin Research, 1066 CX Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Scheeren+FA%22">Scheeren FA</searchLink>; Department of Dermatology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Verdoes+M%22">Verdoes M</searchLink>; Department of Medical Biosciences, Institute for Chemical Immunology, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Vidarsson+G%22">Vidarsson G</searchLink>; Sanquin Research, 1066 CX Amsterdam, The Netherlands.; Department of Biomolecular Mass Spectrometry and Proteomics, Utrecht Institute for Pharmaceutical Sciences and Bijvoet Center for Biomolecular Research, Utrecht University, 3508 TC Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Kuijl+CP%22">Kuijl CP</searchLink>; Department of Medical Microbiology and Infection Control, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22den+Haan+JMM%22">den Haan JMM</searchLink>; Department of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, 1081 HV Amsterdam, The Netherlands.
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  Data: <searchLink fieldCode="JN" term="%229010319%22">Bioconjugate chemistry</searchLink> [Bioconjug Chem] 2024 Nov 20; Vol. 35 (11), pp. 1805-1814. <i>Date of Electronic Publication: </i>2024 Nov 07.
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