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Investigating the possible mechanism of Cornus officinalis in the therapy of ischemic stroke by UHPLC-Q-TOF-MS, network pharmacology, molecular docking, and experimental verification.

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Title: Investigating the possible mechanism of Cornus officinalis in the therapy of ischemic stroke by UHPLC-Q-TOF-MS, network pharmacology, molecular docking, and experimental verification.
Authors: Zhang Y; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450008, PR China. Electronic address: Zhangyantbr@163.com., Yuan PP; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450008, PR China; The Engineering and Technology Center for Chinese Medicine Development of Henan Province, Zhengzhou, 450046, PR China. Electronic address: 15136153630@163.com., Li PY; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450008, PR China. Electronic address: lipanying2020@163.com., Zheng YJ; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450008, PR China. Electronic address: zyj18790251004@163.com., Li SF; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450008, PR China. Electronic address: l1023823585@163.com., Zhao LR; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450008, PR China. Electronic address: 13569672195@163.com., Ma QY; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450008, PR China. Electronic address: 1617484482@qq.com., Cheng JL; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450008, PR China. Electronic address: 17634619098@163.com., Ma JS; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450008, PR China. Electronic address: m2587118470@163.com., Feng WS; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450008, PR China; The Engineering and Technology Center for Chinese Medicine Development of Henan Province, Zhengzhou, 450046, PR China; Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases Co-constructed By Henan Province & Education Ministry of PR China, Zhengzhou, 450008, PR China. Electronic address: fwsh@hactcm.edu.cn., Zheng XK; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450008, PR China; The Engineering and Technology Center for Chinese Medicine Development of Henan Province, Zhengzhou, 450046, PR China; Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases Co-constructed By Henan Province & Education Ministry of PR China, Zhengzhou, 450008, PR China. Electronic address: zhengxk.2006@163.com.
Source: Journal of ethnopharmacology [J Ethnopharmacol] 2025 Feb 10; Vol. 338 (Pt 2), pp. 119072. Date of Electronic Publication: 2024 Nov 08.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Sequoia Country of Publication: Ireland NLM ID: 7903310 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7573 (Electronic) Linking ISSN: 03788741 NLM ISO Abbreviation: J Ethnopharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1872-7573
DOI:10.1016/j.jep.2024.119072